Dihydromyricetin (DHM) from the Japanese raisin tree carries a rich history in traditional medicine. It has traditional applications in mitigating upset stomachs and purportedly easing hangover symptoms. DHM also finds a place in modern supplements.

DHM from Raison Trees [1]

This article is going to discuss the diverse aspects of DHM. Hope that you can learn about its potential side effects, interactions with medications, etc.

What Are DHM?

Dihydromyricetin (DHM) is a prominent flavonoid compound. It is renowned for its origins in the Japanese raisin tree, termed Hovenia dulcis. You can also find its presence in various other plant sources.

This natural compound also has an alternate name ampelopsin. It holds a distinguished place in traditional medicine, particularly in Asian cultures.

• Antioxidant Powerhouse: DHM showcases robust antioxidant properties. This feature aids in combating oxidative stress and neutralizing free radicals. It potentially benefits overall health as well.
• Hangover Relief: DHM is not only notable for its historical use in traditional medicine. It also finds applications in modern supplements. This remedy alleviates hangover symptoms and settles upset stomachs.
• Liver Protection and Overall Health: DHM can support liver health and function. It has become a subject of ongoing research in liver protection. It is also being researched for its potential to mitigate oxidation and inflammation.

Related reading: Does DHM (Dihydromyricetin) Actually Reduce Hangovers?

Does DHM Have Any Side Effects?

The reported side effects of DHM remain notably limited based on current available research. There are lots of related studies. Most of them are carried out on animals. These experiments consistently illustrate a lack of adverse effects, even when administered at relatively high doses.

Sparse customer reviews note occasional mild discomfort like abdominal discomfort, nausea, or diarrhea. However, these instances are infrequent and largely anecdotal. While human studies on this topic are limited, the developing safety profile shows promise.

In a word, the existing evidence hints at a safety profile for DHM. As the scientific exploration continues, a more thorough understanding of DHM’s safety profile will offer clearer insights.

Can DHM Have Interactions with Medications?

The potential interactions between supplements such as DHM and prescribed medications are a significant concern in healthcare considerations.

There are limited studies examining DHM’s impact on liver enzymes in animal models. Their varying outcomes prompt caution in DHM’s use. Namely, these herbal supplements might influence the liver enzymes responsible for metabolizing medications. This influence may result in altered drug effectiveness or potential toxicity risks.

Thus, it is advisable to seek guidance from healthcare professionals before integrating DHM with prescribed medications. In this way, we can mitigate potential adverse effects and ensure patient safety.

What Is the Recommended Amount of DHM?

Determining the ideal dosage of DHM for human consumption is an ongoing area of research.

Recent animal studies investigating DHM dosages have presented encouraging outcomes. These studies consistently administer high doses of DHM to animal subjects without observable adverse reactions. However, despite these promising findings in animal models, the establishment of precise and safe DHM dosages for human consumption requires further extensive research.

This pursuit aims to enhance safety measures and optimize the advantageous use of DHM across various applications.

How to Get Quality DHM?

Ensuring the quality of DHM requires several factors and reliable suppliers:

–Opt for Reputable Manufacturers:

Select DHM supplements or products from established and reputable manufacturers. Look for companies that operate in certified Good Manufacturing Practice (GMP) facilities. Manufacturers adhering to GMP guidelines ensure stringent quality control measures.

–Thoroughly Examine Product Labels:

Carefully scrutinize product labels to assess the ingredients and purity of DHM-containing supplements. Look for clear and transparent labeling. For instance, check the concentration of DHM per serving, additional additives, and any potential allergens.

Products with detailed and accurate labeling often reflect a commitment to quality and transparency.

–Research Supplier Track Record:

Conduct research on suppliers or manufacturers of DHM-containing products. You can refer to local authorities’ databases or consumer protection agencies. Check for any reported issues or complaints against these suppliers.

Verified positive track records and the absence of regulatory issues work. Such evidences provide confidence in the reliability and quality of the supplier’s offerings.

–Seek Third-Party Testing and Certifications:

Look for DHM supplements that undergo third-party testing by independent laboratories. Certifications or endorsements from reputable third-party organizations attest to the product’s quality, purity, and compliance with safety standards. Products with such certifications often display a higher level of commitment to quality and transparency.

–Consider Customer Reviews and Recommendations:

Explore customer reviews and feedback regarding DHM supplements or products from various suppliers. Genuine customer experiences can offer insights into the product’s efficacy, potential side effects, and overall satisfaction. Positive reviews and recommendations from consumers can guide them towards trustworthy suppliers offering quality DHM products.

–Consult Healthcare Professionals:

Consult healthcare professionals or nutritionists before choosing DHM supplements or putting them into your routine. Be more careful if you have existing health conditions or are taking medications. Healthcare professionals can offer personalized guidance and recommendations tailored to your specific health needs.

Conclusion

Current research and customer reviews suggest DHM is generally safe. Yet, comprehensive human studies are essential for conclusive evidence. As research into DHM continues, its safety profile and potential benefits will likely become clearer. So, it can provide more definitive guidance for consumers.

At Stanford Chemicals Company (SCC), we offer exclusively the finest quality Dihydromyricetin (DHM). Our DHM undergoes meticulous testing procedures to ensure both purity and effectiveness. For further information, please explore our homepage.

Reference:

[1] Raison Trees. (2024, August 9). In Wikipedia. https://en.wikipedia.org/wiki/Hovenia_dulcis

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In recent years, the exploration of natural compounds in the realm of medicinal research has gained significant attention. Among these compounds, dihydromyricetin (DHM) has emerged as a subject of interest.

This article is going to explore its properties in addressing two distinct yet interconnected health concerns: inflammatory diseases and anxiety disorders. Hope that you can have a further understanding of DHM’s uses.

Clinical Researches

What Is Dihydromyricetin (DHM)?

Dihydromyricetin comes from the ampelopsis plant species. It is a flavonoid known for its antioxidant and anti-inflammatory attributes. It has spurred investigations into its potential applications in combating various health issues.

–Antioxidant Powerhouse

One of the standout features is its robust antioxidant capacity. DHM has the ability to scavenge these free radicals. It serves as a potent defender against oxidative stress. Thus, DHM potentially aids in the prevention of various chronic diseases and promotes overall health.

–Anti-Inflammatory Properties

DHM has demonstrated notable anti-inflammatory effects in several studies. DHM has the potential to inhibit inflammatory pathways and reduce inflammation markers. It can manage inflammatory diseases like arthritis, inflammatory bowel diseases, and other systemic inflammatory conditions.

–Liver Protection and Detoxification

Research has indicated DHM properties to protect livers. Namely, it plays a role in safeguarding the liver from damage caused by toxins and oxidative stress. It supports liver function, aids in detoxification processes, and promotes liver health.

–Neuroprotective Effects

The influence of DHM extends to the brain. These are studies highlighting its neuroprotective potential. It has shown promise in protecting neurons from damage and supporting cognitive function. Moreover, DHM’s interaction with neurotransmitter pathways hints at its possible role in managing anxiety and stress-related disorders.

Related reading: DHM Dihydromyricetin: The Hangover Helper You Need

How Can Dihydromyricetin (DHM) Alleviate Inflammatory Diseases?

DHM shows new potential in the realm of medicinal research. Here are two notable examples:

Inflammation is a natural response by the immune system. It can escalate into chronic conditions if unchecked. DHM has shown promise in mitigating inflammation markers and modulating inflammatory pathways. Thus, DHM offers a glimpse of hope in managing inflammatory diseases.

–Mechanisms:

Research studies have indicated DHM’s ability to hinder the activation of certain inflammatory signaling molecules. By doing so, it potentially curtails the cascade of events that lead to heightened inflammatory responses. This property has attracted attention in the medical community for its possible implications in conditions like arthritis, inflammatory bowel diseases, and other systemic inflammatory disorders. [1]

–Other Potentials:

The anti-inflammatory potential of DHM extends beyond molecular pathways. Studies have observed its ability to reduce oxidative stress, which is a crucial factor in the progression of inflammatory diseases. By combating oxidative damage, DHM demonstrates a multifaceted approach to potentially mitigating the severity of these conditions.

How Does DHM Work in Anxiety Disorder Management?

Anxiety disorders are characterized by excessive worry, fear, and physiological responses. It affects millions worldwide. Emerging research hints at DHM’s capability to influence neurotransmitter activity in the brain. Thus, it serves as a potential treatment avenue for anxiety-related conditions.

–Mechanisms:

Neurotransmitters like GABA (gamma-aminobutyric acid) play a pivotal role in regulating anxiety. DHM has exhibited modulatory effects on GABA receptors, which could contribute to its anxiolytic properties. By enhancing GABAergic transmission, DHM might assist in calming the nervous system and reducing anxiety symptoms. [2]

–Other Potentials:

Furthermore, studies exploring DHM’s impact on brain receptors associated with anxiety responses have revealed promising results. Its interaction with specific neural pathways suggests a potential to alleviate anxiety symptoms by regulating the intricate balance of neurotransmitters involved in mood regulation.

The Need for Further Research

While preliminary findings regarding DHM’s efficacy in addressing inflammatory diseases and anxiety disorders are encouraging, it’s crucial to acknowledge the need for extensive research.

Clinical trials involving human subjects are indispensable to validate the safety, efficacy, and optimal dosage of DHM as a therapeutic agent. Comprehensive studies will offer a clearer understanding of its mechanisms of action and its potential side effects.

Conclusion: A Glimpse of Promise

The evolving landscape of natural compounds in healthcare continues to unravel potential solutions for prevalent health concerns. Dihydromyricetin, with its anti-inflammatory and potential anxiolytic properties, stands at the threshold of therapeutic advancement.

The journey of DHM from botanical origins to clinical applications holds promise in reshaping the approach to managing inflammatory diseases and anxiety disorders. While the initial research showcases its potential, further exploration and rigorous scientific inquiry are imperative to harness its full therapeutic potential and pave the way for its integration into mainstream healthcare practices.

As research advances, the potential of dihydromyricetin may offer hope for individuals grappling with the burdens of inflammatory diseases and anxiety disorders, presenting a natural alternative in the pursuit of improved health and well-being. For more information, please check our homepage at https://www.stanfordchem.com/.

Reference:

[1] Sun Y, Liu S, Yang S, Chen C, Yang Y, Lin M, Liu C, Wang W, Zhou X, Ai Q, Wang W, Chen N. Mechanism of Dihydromyricetin on Inflammatory Diseases. Front Pharmacol. 2022 Jan 18;12:794563. doi: 10.3389/fphar.2021.794563. PMID: 35115939; PMCID: PMC8804380.

[2] Dr Jing Liang (2021, January 29). Dihydromyricetin shows promise as an anxiety disorder treatment. Research Outreach. Retrieved December 27, 2023, from https://researchoutreach.org/articles/dihydromyricetin-shows-promise-anxiety-disorder-treatment/

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Dihydromyricetin (DHM) has emerged as a subject of growing interest in clinical research due to its diverse pharmacological properties and potential therapeutic applications. Current investigations are shedding light on its promising implications across various health conditions. This condition paves the way for potential clinical uses and future directions in medical practice.

Research and Innovations

This article is going to discuss the features and uses of DHM. Hope that you can have a better comprehensive understanding.

What Is Dihydromyricetin (DHM)?

Dihydromyricetin (DHM) is a natural flavonoid compound. It is derived from certain plant sources, notably from the Hovenia Dulcis tree. It’s recognized for its various pharmacological properties and has gained attention for its potential health benefits.

DHM possesses several notable characteristics:

1. Antioxidative Properties: It exhibits strong antioxidative effects, so it helps to neutralize free radicals in the body, and reduces oxidative stress and potential cell damage caused by reactive oxygen species.
2. Anti-inflammatory Activity: DHM demonstrates anti-inflammatory properties. Thus, it may help alleviate inflammation-related issues by modulating the body’s inflammatory responses.
3. Hepatoprotective Effects: It’s been studied for its potential to protect the liver from damage caused by toxins or alcohol consumption. DHM shows promise in supporting liver health and mitigating liver damage.
4. Metabolic Effects: Recent research indicates DHM’s role in influencing metabolic processes. It’s being investigated for its potential in regulating glucose metabolism, improving insulin sensitivity, and its effects on lipid metabolism.

Further research is ongoing to ascertain its effectiveness and optimal usage in clinical settings.

Related reading: DHM Dihydromyricetin: The Hangover Helper You Need

What Are the Clinical Uses of Dihydromyricetin (DHM)？

The clinical uses of DHM are still being extensively researched and explored. Ongoing studies and preliminary research suggest several potential clinical uses for DHM:

–Metabolic Disorders:

DHM is able to regulate metabolic parameters. That has attracted attention in addressing conditions like diabetes, obesity, and dyslipidemia. Clinical studies exploring its impact on insulin sensitivity, glucose regulation, and lipid metabolism are underway. It also has potential as an adjunct therapy for managing metabolic disorders.

In the realm of diabetes, early research has shown promising outcomes related to DHM’s influence on insulin sensitivity. Studies suggest that DHM might assist in enhancing insulin sensitivity, a critical aspect of managing diabetes. By potentially improving the body’s response to insulin, DHM could offer a pathway toward better glycemic control and, in turn, help regulate blood sugar levels more effectively.

Moreover, investigations into DHM’s effects on glucose regulation have yielded intriguing results. Preliminary studies hint at its ability to modulate glucose metabolism, potentially contributing to maintaining optimal blood glucose levels. This avenue of research presents a promising prospect for individuals grappling with diabetes or those at risk of developing the condition.

–Liver Health:

There is much more research focusing on DHM’s effects on liver-related issues, particularly non-alcoholic fatty liver disease (NAFLD) because DHM has the capacity to mitigate hepatic steatosis and reduce inflammation in the liver. Clinical trials investigating its role in liver health and potential applications in liver disease management are ongoing.

NAFLD is a prevalent liver condition. NAFLD is characterized by the accumulation of fat in the liver cells. This condition often occurs in individuals without excessive alcohol consumption. DHM has emerged as a potential therapeutic agent due to its observed effects on mitigating hepatic steatosis. Preliminary research suggests that DHM might hold promise in reducing the buildup of fat in liver cells, which is a crucial step in managing NAFLD.

Moreover, the compound’s anti-inflammatory properties have been of particular interest in the context of liver health. Inflammation plays a pivotal role in the progression of liver diseases, including NAFLD. DHM’s potential to reduce inflammation in the liver has sparked clinical trials aiming to delve deeper into its mechanisms and effectiveness in attenuating liver inflammation.

–Anti-inflammatory Properties:

DHM’s anti-inflammatory characteristics have implications for conditions associated with chronic inflammation, such as metabolic syndrome and related disorders. Clinical studies aim to elucidate its impact on inflammatory markers and its role in reducing systemic inflammation.

–Neuroprotective Potential:

Preliminary research suggests DHM’s neuroprotective properties. That means it has the potential to address neurological conditions. Clinical investigations focusing on its effects on neurodegenerative diseases and cognitive health are in progress, exploring its possible therapeutic role.

–Safety and Tolerance:

Ongoing clinical trials are assessing DHM’s safety profile, including its dosage, potential side effects, and long-term safety. Understanding its pharmacokinetics and ensuring its tolerability in various patient populations is critical for its clinical translation.

However, while the findings above are promising, comprehensive clinical trials elucidating DHM’s efficacy, safety profile, and optimal usage in varied patient populations are still needed for clinical practice. Continued research endeavors will shape its potential as a valuable therapeutic tool in addressing a spectrum of health conditions.

Conclusion

Dihydromyricetin (DHM) stands at the forefront of clinical exploration due to its various pharmacological properties and therapeutic applications. As research continues to unravel its diverse mechanisms and effects, DHM shows promising prospects across various health conditions. Its antioxidative, anti-inflammatory, hepatoprotective, and metabolic-regulatory attributes have sparked keen interest in the medical community.

Stanford Chemicals Company (SCC) exclusively offers top-tier Dihydromyricetin (DHM) and firmly backs our product’s quality. Our DHM is produced within the United States. These products undergo rigorous testing protocols to ensure unmatched purity and effectiveness. Feel free to reach out to us if you’re interested.

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We’ve all been there—waking up after a night of celebration only to be greeted with the dreaded hangover. The pounding headache, queasy stomach, and overall feeling of exhaustion can put a damper on your day. While there’s no magical cure for a hangover, there is a natural extract that may help alleviate some of those symptoms. Enter DHM Dihydromyricetin, the hangover helper you need.

Excessive Drinking

Understanding DHM Dihydromyricetin

DHM is derived from the Japanese Raisin Tree (Hovenia dulcis) and has long been used in traditional medicine for its potential to support liver health and ease the aftereffects of excessive alcohol consumption. Recent scientific research has shed light on its mechanisms of action and its ability to provide relief from hangover symptoms. Let’s dive into the reasons why DHM is gaining popularity as a go-to hangover remedy.

Related reading: Does DHM (Dihydromyricetin) Actually Reduce Hangovers?

DHM

Mechanisms of DHM Dihydromyricetin

–Enhanced Alcohol Metabolism

One of the primary causes of hangovers is the accumulation of acetaldehyde, a toxic byproduct of alcohol metabolism. DHM has been shown to enhance the breakdown of acetaldehyde, helping the body process alcohol more efficiently. By promoting faster metabolism, it may reduce the duration and severity of hangover symptoms, allowing you to bounce back more quickly.

–Reduced Inflammation

Alcohol consumption can lead to increased inflammation in the body, contributing to hangover symptoms such as headaches and body aches. DHM has demonstrated anti-inflammatory properties, helping mitigate inflammation and reduce discomfort. By soothing the inflammatory response, it provides relief from these nagging hangover symptoms and supports a quicker recovery.

–Antioxidant Protection

Alcohol consumption generates free radicals in the body, leading to oxidative stress and cell damage. DHM exhibits strong antioxidant properties, helping neutralize these free radicals and reduce oxidative stress. By providing antioxidant protection, it contributes to overall health and aid in the recovery process after a night of indulgence.

–Liver Detoxification

Excessive alcohol intake puts a significant strain on the liver, leading to liver damage and compromised detoxification processes. DHM has been found to have hepatoprotective effects. It can enhance the activity of detoxifying enzymes, reduce inflammation in the liver, and provide antioxidant support, all of which contribute to a healthier liver and more efficient detoxification processes. Besides, DHM has shown potential in regulating cholesterol levels by reducing LDL (bad cholesterol) and increasing HDL (good cholesterol) levels, thus helping maintain healthy cholesterol levels.

–Improved Cognitive Function

The neuroprotective effects of DHM have also attracted attention from researchers. DHM has shown promising results in protecting brain cells from damage caused by oxidative stress and neurotoxic substances. It may help enhance cognitive function, improve memory, and even have potential applications in the prevention and treatment of neurodegenerative diseases.

While more research is needed to fully understand the extent of its neuroprotective effects, DHM’s properties make it an intriguing candidate for neurological health.

Incorporating DHM Dihydromyricetin into Your Routine

DHM is available in supplement form, making it convenient to incorporate into your routine. When choosing a DHM supplement, be sure to select a reputable brand that offers a high-quality product. Follow the recommended dosage instructions provided by the manufacturer, and if you have any underlying health conditions or are taking medications, it’s always best to consult with a healthcare professional before starting any new supplement regimen.

Remember, while DHM can support your body’s recovery after drinking, it’s important to consume alcohol responsibly and in moderation. It is not a license to overindulge but rather a natural aid to help your body recover more efficiently.

Conclusion

In a word, DHM Dihydromyricetin offers potential relief from hangover symptoms through enhanced alcohol metabolism, reduced inflammation, antioxidant protection, liver support, and improved cognitive function. Consider adding DHM to your hangover recovery toolkit and embrace the potential benefits of this natural extract. Also, please stay hydrated, eat nourishing foods, and get plenty of rest to aid in your recovery.

Stanford Chemicals Company (SCC) provides quality Dihydromyricetin (DHM) and stands behind our product. Our DHM products are rigorously tested for purity and effectiveness. For more information, please check our homepage.

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Dihydromyricetin (DHM, or Ampelopsin) is a herbal hangover treatment. It is a special type of flavonoid extracted from the oriental raisin trees. Dihydromyricetin has been used as traditional medicine for alcohol-related diseases in China, Japan, and other parts of Asia, and it received popularity in the West recently.

Dihydromyricetin stands out for its anti-alcohol effect. It could relieve hangover symptoms by promoting alcohol metabolism and enhancing the liver. DHM also has potential effects on alcohol addiction and other alcohol-related illnesses. Dihydromyricetin has anti-oxidation, anti-inflammation, and anti-tumor effects as well. Let’s discuss the strong anti-alcohol effect of this natural vine tea extract in detail.

2.   Does DHM (Dihydromyricetin) actually reduce hangovers?

Alcohol-related diseases have dogged us for years. According to World Health Organization, 5.1% of the global burden of disease and injury is attributable to alcohol [1]. There are 88, 000 alcohol-related deaths in the U.S. and 3 million deaths around the world every year [2]. Not to mention, drunkenness could trigger unpleasant feelings including headache, nausea, vomiting, anxiety, clumsiness, and disordered speech.

Thanks to its anti-alcohol effect and hepatoprotective feature, dihydromyricetin can reduce these symptoms in the following ways:

• Reducing alcohol level:

Dihydromyricetin enhances the performance of two alcohol-eating enzymes, so the alcohol intoxication level is reduced more quickly and efficiently.

Excessive consumption of alcohol leads to an excessive amount of ethanol and acetaldehyde, which increase the burden on livers and accumulate toxic byproducts. Two enzymes, ADH and ALDH, help your body to break down them. DHM helps produce more ADH and ALDH and increases their activities, so alcohol inside would be reduced faster.

• Avoiding liver damage

Potential liver-related damage can be avoided because dihydromyricetin eases the burden of the liver and reduces toxic products in the liver.

For one thing, DHM reduces the burden on the liver by breaking down ethanol and acetaldehyde faster. For another, DHM reduces the fat accumulation and inflammation elements in the liver. Fat increases the possibility of liver diseases such as cirrhosis. Inflammation factors like cytokines bring about cellular damage to the liver and other organs. Such damage would be avoided due to DHM.

• Curing alcohol withdrawal symptoms

There is a large possibility that DHM helps to cure alcohol addiction and withdrawal diseases like anxiety, tolerance, and seizures.

3.   Is dihydromyricetin safe?

Dihydromyricetin is quite safe to take. First, it has been used as a natural hangover treatment for over 500 years in Asia. There is no side effect report in academic research on animals and human beings since DHM has been applied to reduce hangovers. Additionally, you could find thousands of positive reviews of DHM-contained hangover supplements. However, please use DHM properly and drink alcohol wisely.

4.   How do you use dihydromyricetin powders?

Based on current research on animals, the recommended dosage of dihydromyricetin range is 80-1200mg, and the best dosage of DHM is around 300mg. However, healthier drinking habits work much better. Please drink more water and have something to eat before dining out.

The best time to use dihydromyricetin varies. If you use DHM as prevention, it is recommended to take the herbal supplement 30 minutes before you drink alcohol. If you take it to reduce hangovers, it is always the best time. DHM can do better work in your sleep.

5.   Conclusion

The article above offers a detailed discussion about the effect, usage, and safety of dihydromyricetin. Hope you can have a better understanding of DHM and its effect on drunkenness. Stanford Chemicals is a leading supplier of the most effective hangover treatment. DHM products are stored in cool and dry places, and they are protected from direct sunlight and heat. The specifications of our products are listed as follows.

Table 1 Dihydromyricetin Specifications

Furthering Reading: Everything You Need to Know About Dihydromyricetin

Reference:

[1] World Health Organization (2022, May 9). Alcohol. Retrieved January 16, 2023, from https://www.who.int/news-room/fact-sheets/detail/alcohol

[2] World Health Organization. Global Status Report on Alcohol and Health. 2014. Geneva, Switzerland: World Health Organization; 2014.

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What Are Flavonoids?

Flavonoids are chemicals produced by plants, having a wide range of benefits to both the plant and prospective immunocompromised patients. Some of these functions include: protecting plants from stress and contributing to the smell and color of fruit and flowers. To the human body, they help in the regulation of cellular activity and wrestle against free radicals responsible for oxidative stress. Flavonoids are more like antioxidant agents.

What Does Dihydromyricetin Treat?

The usefulness of Dihydromyricetin cuts across, improving a wide range of both medical and even mental complications. This includes its ability to cure infections inflicted by parasites and counteract the harmful effect of drug abuse or overdose. They are also effective in treating anxiety, depression, and other mental issues.

Other functions include regulation of cancer activity, cell death mediating activity, metabolism mediating activity, neuroprotective activity, and anti-inflammatory activity. Dihydromyricetin activates enzymes such as alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH), which are responsible for breaking down and metabolizing alcohol faster, hence its characteristics preventing hangovers.

Chemical Properties of Dihydromyricetin

PubChem CID: 161557

Molecular Formula:  C₁₅H₁₂O₈

Molecular Weight: 320.25

Structure:

How Do You Use Dihydromyricetin Powders?

The quickest way to start feeling the impact of dihydromyricetin is by consuming the powdered state. This rapidly enhances its potency. The ingestion method is a very effective way to take in the drug. You can dissolve some milligrams of the DHM powder in a glass of juice of your choice and then drink.

You can also dissolve the powder in water before consumption in some cases. In this way, however, you get to taste the herb, and it may not precisely give that sweet taste you’d probably hoped for. It is advisable to take the mixture at home and rest afterward.

Recommended dosage:  You can consume 300-4000mg of dihydromyricetin powder.

How Do You Use Dihydromyricetin Capsules or Pills?

If you’re comfortable swallowing capsules and pills, you may consider taking this option. DHM pills or capsules may not be as fast as the DHM powder, but the effects vary. The capsules are designed to be easy to swallow with water or juice.

You can take the dihydromyricetin pills or capsule anywhere: in a gathering of friends, in your home, or workplace, or just wherever you feel comfortable. Since these are capsules, it would take your system some time to dissolve when you swallow them. Therefore, it takes a while to see its effect.

Recommended dosage: 1-2 pills are okay for consumption, depending on the case.

For Hangover Prevention, Should I Take DHM Before or After Drinking?

It is best to take the drug just immediately after drinking. In this way, you get to feel the drug’s effect more intensely. Some persons, in several reviews, have attested to the effective working power of the drug, rating it about 97-100% effective. It is important to note that DHM will not stop you from getting drunk. It only reduces the impact of alcohol.

How Safe is Dihydromyricetin?

There’s no need to be bothered about how safe consuming this drug is. The herb has been used for ages, in some parts of the world, and all the while, it has worked well, without posing severe health implications.

However, this is not to say that there may not arise cases where dihydromyricetin may tend to cause some side effects. It is just that generally, these side effects are both rare and mild. However, should you experience any form of reaction just after consuming the drug, it is advisable to visit a doctor.

Conclusion

Dihydromyricetin is an anti-oxidation drug that reduces blood glucose levels and protects the liver. At Stanford Chemicals, we sell high-quality Dihydromyricetin (DHM) powders following the best standard practices to ensure that they are tested rigorously for purity and effectiveness. Contact us to get your Dihydromyricetin powder with a purity above 98%, or call us at (949) 812 6690 or (949) 468 0555 to place your order.

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The Biological Experiment of Dihydromyricetin Extract

It is reported that on January 13, 2012, the Oriental Morning Post reported that researchers at the University of California in Los Angeles developed a new drug using Fructus aurantii extract, which could be injected into mice to relieve alcohol, which could relieve the “top” symptoms in a short period of time.

The researchers used the Fructus aurantii extract Dihydromyricetin (DHM) to observe the antialcoholism efficacy of different medicinal herbs. They let the mice drink a certain amount of alcohol in 2 hours, which was equivalent to drinking 15 to 20 bottles of beer. As expected, most of the mice were drunk and the rest had not been touched even after being knocked down. Within 1 hour, the symptoms of drunkenness began to weaken, and mice gradually resumed their control of the body.

In the second part of the experiment, the researchers injected the mice with alcohol and injected them with dihydromyricetin, and found that the mice increased their ability to control their own behavior, delayed the onset of drunken symptoms, and recovered about 15 minutes after drunkenness.

Moreover, rats injected with dihydromyricetin for two days in a row were less excited, had spasticity and other drunken symptoms, and were not “greedy”, which meant that dihydromyricetin had a certain inhibitory effect on alcohol addiction.

It is observed that the effect of dihydromyricetin is effective. Drinking and ingestion of rattan tea containing dihydromyricetin can quickly remove alcohol and make the problem of hangovers effectively restrained.

Antibacterial Effect of Dihydromyricetin Extract

The pharmacological experiments showed that Dihydromyricetin had bacteriostasis effect on Bacillus subtilis, Staphylococcus aureus, Salmonella, Escherichia coli, bacilli, Saccharomyces cerevisiae, myxomyces, Penicillium, Aspergillus niger, Aspergillus flavus, Mucor, and Rhizopus, especially gram positive, gram negative cocci.

It has many functions:

1) Dihydromyricetin can Clear the free radical in the body and Antioxidation:

The vine tea extract can effectively level down lipid peroxidation. It can prevent the oxidative damage of antioxidase in the body caused by the free radical. Then it can improve the oxidation resistance of the human body;

2) Dihydromyricetin can Antibiotic Action:

The vine tea extract has the strong inhibitory action of staphylococcus aureus and Bacillus subtilis. It also has inhibitory action of Aspergillus flavus, Aspergillus niger, Penicillium, and Alternaria. Dihydromyricetin has the inhibitory action of Staphylococcus aureus, Staphylococcus aureus(S. aureus), and Pseudomonas aeruginosa.

3) Dihydromyricetin can Protect the Liver:

Dihydromyricetin has a strong inhibitory action on the rise of ALT and AST in the blood Serum. It can lower the total bilirubin in the blood serum. So it has the strong action of lowing the aminotransferase and jaundice. The vine tea extract can restrain liver fibrosis in the rat.

4) Dihydromyricetin can Reduce the levels of blood sugar and blood fat:

Dihydromyricetin can reduce the blood fat levels in the mouse. It can decrease the damage to liver cells caused by high blood fat levels and improve the antioxidation ability. At the same time, it can lower the levels of high blood sugar.

5) Dihydromyricetin can Anti-inflammation:

The vine tea extract can effectively restrain the mouse pinna swelling caused by xylene. It can also restrain the writhing response in the mouse caused by acetic acid.

6) Dihydromyricetin can Anti-tumor:

The vine tea extract has effectively restrained to cell proliferation of some tumor cells.

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1. Drink water

To wake up feeling refreshed the next day after drinking, make sure you don’t dehydrate before you start drinking. Drinking prevents the production of a chemical called vasopressin. This helps our kidneys to deliver water directly to the bladder, rather than to absorb it into your body. In fact, drinking means that you drain more than four times the water than usual. This can lead to dehydration, which is the main cause of hangover headaches and dry mouth. So before you start drinking, your goal is to drink more water. You can drink up to eight glasses of water a day.

2. Eat greasy food

Food helps to slow down the absorption of alcohol. In particular, if you eat greasy food before drinking, fat will line up on the wall of your stomach. This will help slow down the speed at which alcohol enters the bloodstream, which means that you need more time to get drunk. You can also drink a full glass of milk or olive oil, which may help.

3. Drink coffee and take aspirin

A  study published in the Journal PIOS ONE in 2010 found that caffeine in coffee and anti-inflammatory ingredients in aspirin reacts to compounds of ethanol (pure alcohol). Ethanol causes a headache due to the chemical acetate.
However, it is important to know that coffee does dehydrate. However, it can cause an increase in adrenaline, which will give rise to false energy. Be careful when drinking coffee and taking painkillers at the same time.

4. Take a bath

Taking a cold bath can refresh your mind and make you feel active. You can also try switching between hot and cold water. But be careful when you do this because it will impact your body and cause more damage.

5. Exercise

When you exercise, endorphins are released to boost your mood. It also helps to consume the calories you get when you drink alcohol. However, make sure you drink water while exercising so that you don’t become more dehydrated. Exercise may require some willpower, but it will certainly help improve your body and mind.

6. Take a break

Sleeping for a while will help your body recover. An extra hour or two in bed will help your body get the rest it needs. You may need to postpone your plan for a day. However, if you need to work, you’d better take an aspirin and go back to work.

7. Try traditional Chinese medicine therapy

Maybe you feel like a witch stirring her beer, but Chinese medicine therapy can help you replenish lost nutrients. Dihydromyricetin can effectively help relieve hangover headaches.

8. Keep drinking water or juice

You still need to keep your body hydrated. Supplementing your body with water or fruit, Vitamin C, or vegetable juice will help you regain the balance you want. It is a good choice to add lemon juice to warm water.

9. Eat toast or crackers

In hangovers, original bagels, toast, and biscuits are good choices. Although they may not be the most delicious snacks, chances are you don’t like them. But hangovers can cause your blood sugar levels to drop – pure carbohydrates will help raise your blood sugar and stop vomiting.

The post How to Cure a Hangover appeared first on Stanford Chemicals.

Dihydromyricetin, a special flavonoid extracted from Ampelopsis, is known as “soft gold in flavonoids”.
This kind of substance has many peculiar effects, such as scavenging free radicals, antioxidation, antithrombotic, anti-tumor, and anti-inflammatory. And dihydromyricetin is a more special kind of flavonoid.

What are the characteristics of Dihydromyricetin?

1, The general flavonoids are basically insoluble in water, soluble in ethanol, and dihydromyricetin
is easy to dissolve in hot water, that is to say, as long as the dihydromyricetin in rattan tea can be soaked in open water, the efficacy is better.

2, In addition to the general effect of flavonoids, HMP also has the effect of relieving alcoholism, preventing alcoholic liver, and fatty liver, inhibiting the deterioration of hepatocytes, and reducing the incidence of liver cancer.

3, Dihydromyricetin has a small molecular weight, which is easier to penetrate the blood-brain barrier and works faster.

What are the benefits of Dihydromyricetin?

Antibacterial effect:

The pharmacological experiments showed that Dihydromyricetin had a bacteriostasis effect on Bacillus subtilis, Staphylococcus aureus, Salmonella, Escherichia coli, bacilli, Saccharomyces cerevisiae, myxomycetes, Penicillium, Aspergillus niger, Aspergillus flavus, Mucor, and Rhizopus, especially gram-positive, gram-negative cocci.

The regulation of blood sugar and blood lipid:
Dihydromyricetin could obviously inhibit the increase of blood glucose induced by four oxalacil, adrenalin, and streptozotocin. At the same time, the level of serum insulin was increased. The infiltration of lymphocytes in the pancreas tissue was significantly reduced, the inflammatory response was obviously reduced, and the number of islets increased significantly.

Liver protection:

Dihydromyricetin can protect the liver, accelerate the decomposition of acetaldehyde and become a non-toxic substance, and reduce the damage to liver cells. In addition, Dihydromyricetin can improve the activity of serum lactate dehydrogenase and inhibit the formation of collagen fibers in liver M cells, thus playing a role in protecting the liver, greatly reducing the damage of ethanol to the liver, so that the normal state of the liver is rapidly recovered. The Micro herb test showed that Dihydromyricetin could protect the liver, accelerate the rapid decomposition of acetaldehyde and become a nontoxic substance and reduce the damage to liver cells. Dihydromyricetin is effective. It is a good product to protect the liver and liver, relieve alcoholism, and sober up.

Antioxidation:
Dihydromyricetin, with a purity of 98%, can obviously inhibit the formation of malondialdehyde (MDA) in the myocardium, liver, and brain homogenate, and increase the effectiveness of the inhibition of MDA formation with the increase of the concentration of Dihydromyricetin, and the clearance rate of the two benzene three nitrophenyl hydrazine (DPPH) free radical in the test system. Dihydromyricetin can obviously inhibit the formation of MDA in oil and increase the antioxidant effect and has a strong antioxidant effect on animal oil and vegetable oil.

Antitumor effect:
In recent years, anti-tumor pharmacodynamic studies have found that one of the active components is Ampelopsis, a small molecule compound that has a strong anti-cancer effect. The antitumor effect in vitro shows that the compound can improve the therapeutic effect of the tumor and improve the patient’s living body disease by inhibiting the growth of tumor vessels and regulating the immune function of the cell. The tumor suppressor effect is obvious in the model test of leukemia and nasopharyngeal carcinoma.

Can Dihydromyricetin Relieve Alcohol?

Researchers say that dihydromyricetin can block the most important inhibitory receptor in the central nervous system, namely, GABAA receptor. This antialcoholism principle is the same as that of some promising antialcoholism drugs now, but the latter can cause convulsions. In the latest issue of the Journal of Neurology, the researchers published a report: “Take dihydromyricetin in alcohol, and you will not be addicted to alcohol.” However, this research achievement will take some time to develop antialcoholism drugs.

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