Everything You Need to Know About Dihydromyricetin
Dihydromyricetin, a special flavonoid extracted from Ampelopsis, is known as “soft gold in flavonoids”.
This kind of substance has many peculiar effects, such as scavenging free radical, antioxidation, antithrombotic, anti-tumor and anti-inflammatory. And dihydromyricetin is a more special kind of flavonoids.
What are the characteristics of Dihydromyricetin?
1, the general flavonoids are basically insoluble in water, soluble in ethanol, and dihydromyricetin
is easy to dissolve in hot water, that is to say, as long as the dihydromyricetin in rattan tea can be soaked with open water, the efficacy is better.
2, in addition to the general effect of flavonoids, HMP also has the effect of relieving alcoholism, preventing alcohol liver, fatty liver, inhibiting the deterioration of hepatocyte and reducing the incidence of liver cancer.
3, Dihydromyricetin has a small molecular weight, which is easier to penetrate the blood-brain barrier and work faster.
The pharmacological experiments showed that Dihydromyricetin had bacteriostasis effect on Bacillus subtilis, Staphylococcus aureus, Salmonella, Escherichia coli, bacilli, Saccharomyces cerevisiae, myxomyces, Penicillium, Aspergillus niger, Aspergillus flavus, Mucor and Rhizopus, especially gram positive, gram negative cocci.
The regulation of blood sugar and blood lipid:
Dihydromyricetin could obviously inhibit the increase of blood glucose induced by four oxalacil, adrenalin, and streptozotocin. At the same time, the level of serum insulin was increased. The infiltration of lymphocytes in the pancreas tissue was significantly reduced, the inflammatory response was obviously reduced, and the number of islets increased significantly.
Dihydromyricetin can protect the liver, accelerate the decomposition of acetaldehyde and become a non-toxic substance, and reduce the damage to liver cells. In addition, Dihydromyricetin can improve the activity of serum lactate dehydrogenase and inhibit the formation of collagen fibers in liver M cells, thus play a role in protecting liver, greatly reducing the damage of ethanol to the liver, so that the normal state of the liver is rapidly recovered. The Micro herb test showed that Dihydromyricetin could protect the liver, accelerate the rapid decomposition of acetaldehyde and become a nontoxic substance and reduce the damage to liver cells. Dihydromyricetin is effective. It is a good product to protect the liver and liver, relieve alcoholism and sober up.
Dihydromyricetin, with a purity of 98%, can obviously inhibit the formation of malondialdehyde (MDA) in the myocardium, liver and brain homogenate, and increase the effect of the inhibition of MDA formation with the increase of the concentration of Dihydromyricetin, and the clearance rate of the two benzene three nitrophenyl hydrazine (DPPH) free radical in the test system. Dihydromyricetin can obviously inhibit the formation of MDA in oil and increase the antioxidant effect, and has a strong antioxidant effect on animal oil and vegetable oil.
In recent years, anti-tumor pharmacodynamic studies have found that one of the active components is Ampelopsis, a small molecule compound has a strong anti-cancer effect. The antitumor effect in vitro shows that the compound can improve the therapeutic effect of the tumor and improve the patient’s living body disease by inhibiting the growth of tumor vessels and regulating the immune function of the cell. The tumor suppressor effect is obvious in the model test of leukemia and nasopharyngeal carcinoma.
Researchers say that dihydromyricetin can block the most important inhibitory receptor in the central nervous system, namely, GABAA receptor. This antialcoholism principle is the same as that of some promising antialcoholism drugs now, but the latter can cause convulsions. In the latest issue of the Journal of Neurology, the researchers published a report: “take dihydromyricetin in alcohol, and you will not be addicted to alcohol.” However, this research achievement will take some time to develop antialcoholism drugs.