040-000-290 Piperaquine, CAS 4085-31-8

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Synonyms Piperaquine Phosphate, Sotalol Hydrochloride, Piperaqu, Piperaquinoline
Keywords Malaria, artemisinin, Artemisia Annua Extract, COVID-19, SARS-CoV-2
Related products  Artemisinin, hydroxychloroquine

Stanford Chemicals Company is a Piperaquine supplier in USA. We offer the small Piperaquine phosphate sample and bulk powders.



Piperaquine Specifications

Product Name Piperaquinoline
CAS Registry Number 4085-31-8
Molecular Formula C29H32Cl2N6
Molecular Weight 535.51 g/mol
Purity >99.0 %
Appearance White powder
Shelf life 2 years
Functions highly active against chloroquine-resistant Plasmodium falciparum and Plasmodium vivax

Piperaquine Description

Piperaquine is an antiparasitic drug used in combination with dihydroartemisinin to treat malaria. It is a bis-quinoline compound that inhibits the vitro growth of P. falciparum isolates from malaria-infected patients with IC50s ranging from 11.8-217.3 nM. Piperaquine was developed under the Chinese National Malaria Elimination Programme in the 1960s and was adopted throughout China as a replacement for the structurally similar antimalarial drug chloroquine.

Piperazine phosphate has also recently become a potential drug against COVID-19.



Piperaquine Applications

  • Used as a partner drug for artemisinin combination therapy
  • Potential drug against SARS-COV-2


  1. Akoachere, M., Buchholz, K., Fischer, E., et al. In vitro assessment of methylene blue on chloroquine-sensitive and -resistant Plasmodium falciparum strains reveals synergistic action with artemisinins. Antimicrob. Agents Chemother. 49(11), 4592-4597 (2005).
  2. Davis TM, Hung TY, Sim IK, Karunajeewa HA, Ilett KF (2005). “Piperaquine: a resurgent antimalarial drug”. Drugs. 65 (1): 75–87.
  3. Haldar K, Bhattacharjee S, Safeukui I (2018). “Drug resistance in Plasmodium”. Nature Reviews Microbiology. 16: 156–170.