040-000-292 Arbidol Hydrochloride, CAS 131707-23-8
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| Synonyms | 6-bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylthio)methyl]-1H-indole-3-carboxylic acid |
| Type | Antibiotics, protease, tyrosine kinase inhibitor |
| Keywords | Anti-vierus, COVID-19, antiviral, SARS-CoV-2, anti-infection, anti-influenza |
| Related products | Piperaquine, Chloroquine Diphosphate, Artemisinin, Acrichin Dihydrochloride |
Description
Description
Arbidol Hydrochloride Specifications
| Product Name | Arbidol Hydrochloride |
| CAS Registry Number | 131707-23-8 |
| Molecular Formula | C22H25BrN2O3S•HCl |
| Molecular Weight | 513.9 g/mol |
| Purity | 99.5 % |
| Appearance | White powder |
| Package | 1kg-25kg |
| Shelf life | 2 years |
| Functions | Anti-infection, anti-influenza, anti-vierus |
Arbidol Hydrochloride Description
Arbidol is a broad-spectrum, indole-based antiviral compound that blocks viral fusion with target membranes, prohibiting viral entry into cells. Because arbidol targets a common critical step for viral replication, it is effective against numerous viruses, including influenza A, B, and C and hepatitis B and C (IC50s range from 3-12.5 µg/ml). Besides its antiviral action, arbidol has been reported to produce an immunomodulatory response by inducing interferon production and stimulating the phagocytic function of macrophages.
arbidol hydrochloride
Arbidol Hydrochloride Applications
- Anti-influenza drugs against influenza A and B viruses
- Laboratory research
Reference:
- Kramarev SA, Moshchich AP.[The treatment of influenza and acute respiratory viral infections]. Lik Sprava. 2013 Mar;(2):99-106.
- Kadam RU, Wilson IA. Structural basis of influenza virus fusion inhibition by the antiviral drug Arbidol.Proc Natl Acad Sci U S A 2017 Jan 10;114(2):206-214.
