- 040-000-292 Arbidol Hydrochloride, CAS 131707-23-8
040-000-292 Arbidol Hydrochloride, CAS 131707-23-8
|Type||Antibiotics, protease, tyrosine kinase inhibitor|
|Keywords||Anti-vierus, COVID-19, antiviral, SARS-CoV-2, anti-infection, anti-influenza|
|Related products||Piperaquine, Chloroquine Diphosphate, Artemisinin, Acrichin Dihydrochloride|
Arbidol Hydrochloride Specifications
|Product Name||Arbidol Hydrochloride|
|CAS Registry Number||131707-23-8|
|Molecular Weight||513.9 g/mol|
|Package||1oo mg-100 g|
|Shelf life||2 years|
|Functions||Anti-infection, anti-influenza, anti-vierus|
Arbidol Hydrochloride Description
Arbidol is a broad-spectrum, indole-based antiviral compound that blocks viral fusion with target membranes, prohibiting viral entry into cells. Because arbidol targets a common critical step for viral replication, it is effective against numerous viruses, including influenza A, B, and C and hepatitis B and C (IC50s range from 3-12.5 µg/ml). Besides its antiviral action, arbidol has been reported to produce an immunomodulatory response by inducing interferon production and stimulating the phagocytic function of macrophages.
Arbidol hydrochloride is a non-nucleoside antiviral drug. Arbidol can specifically inhibit the contact, adhesion, and fusion of virus lipid envelope with the host cell membrane by activating the antiviral protein in the host, thereby inhibiting the replication of the virus in host cells.
Arbidol Hydrochloride Applications
- Anti-influenza drugs against influenza A and B viruses
- Laboratory research
- Kramarev SA, Moshchich AP.[The treatment of influenza and acute respiratory viral infections]. Lik Sprava. 2013 Mar;(2):99-106.
- Kadam RU, Wilson IA. Structural basis of influenza virus fusion inhibition by the antiviral drug Arbidol.Proc Natl Acad Sci U S A 2017 Jan 10;114(2):206-214.