040-000-353 Evodiamine, CAS 518-17-2

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Synonyms d-Evodiamine; Isoevodiamine
Source Evodiae feuctu
Keywords Anti-cancer, traditional Chinese medicine, fat uptake
Related products Kojic Acid, Ellagic Acid, Rapamycin


Evodiamine Specifications

Product Name Evodiamine
CAS Registry Number 518-17-2
Molecular Formula C19H17N3O
Molecular Weight 303.36 g/mol
Purity 99 %
Appearance Pale yellow powder
Package 1kg-25kg
Shelf life 2 years
Functions Inhibit the proliferation of a variety of tumor cells, including cervical cancer, colon cancer, lung cancer, melanoma, T lymphocytic leukemia, prostate cancer, and breast cancer

Evodiamine Description

Evodiamine is a yellow flaky crystal with a melting point of 278°C. It is soluble in acetone, slightly soluble in ethanol, ether, and chloroform, and almost insoluble in water, petroleum ether, and benzene. It is weakly alkaline and does not easily form salt. Evodiamine has been biosynthesized. Evodiamine has pharmacological effects such as analgesia, lowering blood pressure, and increased body temperature, and can be used as a diuretic and sweating agent.

Evodiamine (EVO) is a major alkaloid compound extracted from the dry unripened fruit Evodiae fructus (Evodia rutaecarpa Benth., Rutaceae). EVO has a variety of pharmacological activities, such as anti-obesity, anti-allergenic, analgesic, anti-tumor, anti-ulcerogenic, and neuroprotective activities.


Evodiamine Applications:

  • Analytical reagent


  1. Hu Y, Ehli EA, Hudziak JJ, Davies GE (October 2012). “Berberine and evodiamine influence serotonin transporter (5-HTT) expression via the 5-HTT-linked polymorphic region”. The Pharmacogenomics Journal. 12 (5): 372–8.