Ligustrazine Hydrochloride Specifications

Ligustrazine Hydrochloride Description

Ligustrazine (tetramethylpyrazine) inhibits of platelet aggregation, enhances of vessel dilation, increases cerebral blood flow and possesses neuroprotective properties. The injection solution of ligustrazine has been used especially to treat ischemic stroke, coronary heart disease, diabetic nephropathy, and knee osteoarthritis. Ligustrazine was also evaluated in clinical as a remedy for pressure sores, as a salvage agent for patients with non-Hodgkin's lymphoma, as a treatment for bronchial asthma and vertebrobasilar insufficiency.

Ligustrazine Hydrochloride Applications

• Pharmaceutical ingredients are used for contractile stroke, chest pain, swollen pain, headache, hypertension, coronary atherosclerotic heart disease (coronary heart disease), migraine, dilated encephalopathy, etc.

Reference:

1. Liao, S.-L., Kao, T.-K., Chen, W.-Y., et al. Tetramethylpyrazine reduces ischemic brain injury in rats. Neurosci. Lett. 372(1-2), 40-45 (2004).
2. Wang, Y., Fu, Q., and Zhao, W. Tetramethylpyrazine inhibits osteosarcoma cell proliferation via downregulation of NF-κB in vitro and in vivo. Mol. Med. Rep. 8(4), 984-988 (2013).