040-000-335 Dasatinib Monohydrate, CAS 863127-77-9

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Synonyms Dasatinib hydrate; N-[2-Chloro-6-methylphenyl]-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide;
Keywords Anti-aging, cancer, remove senescent cells, treatment of leukemia
Related products Metformin (Hydrochloride), Berberine, Acarbose
Description

Description

Dasatinib Monohydrate Specifications

Product Name Dasatinib Monohydrate
CAS Registry Number 863127-77-9
Molecular Formula C22H28ClN7O3S
Molecular Weight 506.02
Purity >97.0 %
Appearance White powder
Package 1kg-25kg
Shelf life 2 years
Functions Remove senescent cells, treatment of leukemia

Dasatinib Monohydrate Description

Dasatinib monohydrate is an inhibitor of Src family kinases, including c-Abl and Bcr-Abl tyrosine kinase activity. Dasatinib inhibits c-Abl and Bcr-Abl tyrosine kinase activity and shows efficacy against imatinib-resistant Bcr-Abl mutations.

dasatinib monohydrate

Dasatinib Monohydrate Applications

  • Laboratory research
  • Used as a pharmaceutical ingredient of anti-cancer drugs

Reference:

  1. Hořínková J, Šíma M, Slanař O.Prague Med Rep. 2019;120(2-3):52-63.
  2. Shah NP.Drugs Today (Barc). 2007 Jan;43(1):5-12.
  3. Palmer AK, Xu M, Tchkonia T, Kirkland JL.Aging Cell. 2019 Jun;18(3):e12950. doi: 10.1111