040-000-256 Metformin (Hydrochloride), CAS 1115-70-4

SKU: 040-000-256 Category:
Want More Info?





  I would like to join the mailing list to receive updates from Stanford Chemicals.

Synonyms 3-(diaminomethylidene)-1,1-dimethylguanidine, Glucophage
Keywords Type 2 diabetes, blood glucose, PCOS, overweight, obesity
Related products Thiazolidinediones, Berberine, Berberine Hydrochloride, Silybum Marianum Extract
Description

Description

Specifications of Metformin

Product Name Metformin (Hydrochloride)
CAS Registry Number 1115-70-4
Molecular Formula ‎C4H11N5 • HCl
Molecular Weight 165.6
Purity >99%
Appearance White powder
Boiling point 229.23°C
Density 1.0743
Shelf life 2 years
Functions Reduce blood glucose, anti-cancer, treatment of type 2 diabetes and other metabolism diseases

 

Description of Metformin

Metformin is now a first-line agent for the treatment of type 2 diabetes, and can be used alone or in combination with sulfonylureas, thiazolidinediones or other hypoglycemic agents. It can increase the activity of AMPK and reduces blood glucose by more than 50% in mice, according to the research. In recent years, more and more research has focused on the role of metformin in cancer.

Applications of Metformin

  • Treatment of diabetes hyperglycemia, polycystic ovary syndrome, and atherosclerosis
  • Laboratory research

Reference:

  1. Kim, E.K., Lee, S.H., Jhun, J.Y., et al. Metformin prevents fatty liver and improves the balance of white/brown adipose in an obesity mouse model by inducing FGF21. Mediators Inflamm. 5813030, (2016).
  2. Lautatzis, ME; Goulis, DG; Vrontakis, M. Efficacy and safety of metformin during pregnancy in women with gestational diabetes mellitus or polycystic ovary syndrome: a systematic review. Metabolism: clinical and experimental. November 2013, 62 (11): 1522–34.
  3. Dunn CJ, Peters DH. Metformin. A review of its pharmacological properties and therapeutic use in non-insulin-dependent diabetes mellitus. Drugs. May 1995, 49 (5): 721–49.
Submit your review
1
2
3
4
5
Submit
     
Cancel

Create your own review

Metformin
Average rating:  
 1 reviews
by Gary on Metformin

Works for me!