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Hyaluronic Acid

Hyaluronic AcidProduct Name: Hyaluronic Acid
Synonyms: Hyaluronic Acid, Sodium hyaluronate Hyaluronan
CAS: 9067-32-7
MF: (C14H22NNaO11)n
Appearance: White powder
Standard: EP7.0
Read More: http://www.hyaluronicacidsupplier.com
 

Overview

 

Hyaluronic acid, also known as Hyaluronan or Sodium hyaluronate is an anionic (negatively charged), non-sulfated glycosaminoglycan naturally found in the human body. Classified as a polysaccharide (a type of carbohydrate molecule), Hyaluronic Acid is found in the highest concentrations in fluids in the eyes and joints.

 

The Hyaluronic Acid that is used as medicine is extracted from rooster combs or made by bacteria in the laboratory.


A key function of Hyaluronic Acid is to help lubricate, hydrate and stabilize connective tissue and the eyes. It can hold 500 times its own weight of water. In addition, it might affect the way the body responds to injury.

 

Hyaluronic Acid is available in food, cosmetic, eye and injection grade. It is notably used for joint disorders in humans and horses, as well as for cosmetic and eye surgery.


 

Application

 
Food supplements:

Hyaluronic Acid is available in nutritional supplement form.  As we get older, the body's Hyaluronic Acid levels decrease.  Hyaluronic Acid supplements can thus be used to treat or prevent aging-related health problems. 


In addition Hyaluronic Acid supplements can help treat; chronic fatigue syndrome; chronic pain; fibromyalgia and insomnia.


Hyaluronic Acid supplements are also said to improve bone density and protect against osteoporosis, increase muscle strength, and enhance sexual function.


Medical applications:

Hyaluronic Acid is used for various joint disorders, including osteoarthritis. Hyaluronic Acid may help reduce inflammation, relieve pain, restore joint fluids, and protect against cartilage breakdown in osteoarthritis patients. It can be taken orally or injected into the affected joint by a healthcare professional. It works by supplementing the viscosity of the joint fluid, thereby lubricating and cushioning the joint, and thus producing an analgesic effect.


It has been FDA approved and can be used during certain eye surgeries including cataract removal, corneal transplantation, and repair of a detached retina and other eye injuries. It is injected into the eye during the procedure to help replace natural fluids.


Hyaluronic Acid has also been used in the synthesis of biological scaffolds for wound-healing applications. These scaffolds typically have proteins such as fibronectin attached to the hyaluronan to facilitate cell migration into the wound.


Hyaluronan can also be used in anti-adhesive products, which are widely used in pelvic and abdominal surgery to prevent postoperative adhesions.


Cosmetics applications:

Hyaluronic acid’s outstanding moisture retaining ability and viscoelastic properties have established it as a leading ingredient in cosmetic applications. The FDA approved hyaluronan injections for filling soft tissue defects, such as facial wrinkles, lip augmentation, reduction of folds and wrinkles, and removal of scars. It can be injected into the dermis to reduce facial lines and wrinkles as well as scars for longer than when common cosmetic products are applied. There is also better tolerability compared to collagen.


Hyaluronic Acid can be formulated in various cosmetic products such as creams, lotions, serums, shampoos, conditioners, bath oils, foundations, lipsticks or lip balms. It can also be applied to the skin for healing wounds, burns, skin ulcers, and as a moisturizer. Cosmetic products containing Hyaluronic Acid may also protect the skin against UV irradiation due to the free radical scavenging properties of Hyaluronic Acid. .


Equine applications:
Training, competition or aging can lead to degradation of cartilage and the synovial fluid, the shock absorbing fluid in the joints. Hyaluronic Acid improves joint function by lubricating joints, helping to maintain structural integrity, and increasing the thickness level of the synovial fluid. Including Hyaluronic Acid in the management of joint pain may protect the joint by increasing the viscosity of the joint fluid, reducing inflammation and scavenging free radicals. Free radicals are components of cells that can cause damage to the cell.

 

Fermented Product

Grade

MOQ

US$

Inquiry

Food grade

5kg

$500/kg

Ask for a Quotation

Cosmetics grade

5kg

$560/kg

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Eye drops grade

1kg

$2800/kg

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Injection grade

100g

$25000/kg

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Items

Specifications

Appearance

White powder

Infrared absorption spectrophotometry

Ph. Eur. Reference Standards

Appearance of solution

A600nm≤0.01

pH (5mg/mL solution)

5.0-8.0

Intrinsic viscosity

Measured values

Molecular weight

Measured values

Sulfated glycosaminoglycans

≤1%

Nucleic acid

A260nm≤0.5

Protein

≤0.1%

Chlorides

≤0.5%

Iron

≤80ppm

Heavy metals

≤20ppm

Loss on drying

≤20.0%

Bacterial counts

≤100cfu/g

Mold and Yeast

≤100cfu/g

Sodium hyaluronate

95%-105%

Glucuronic acid

≥42.0%