040-000-337 Spermidine Trihydrochloride, CAS 334-50-9

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Synonym Spermidine
Keywords Anti-aging, inhibit neuron synthetase, Alzheimer’s disease
Related products β-Nicotinamide mononucleotide, NMN, Nicotinamide Riboside, NR, Dasatinib Monohydrate
Description

Description

Spermidine Trihydrochloride Specifications

Product Name Spermidine
CAS Registry Number 334-50-9
Molecular Formula C7H19N3
Molecular Weight 145.2 g/mol
Purity 99 %
Appearance White powder
Shelf life 2 years
Functions Induce phagocytosis, Retarded protein aging, Inhibition of neuronal NO synthase (nNOS)

Spermidine Trihydrochloride Description

Spermidine, also known as Spermidine Trihydrochloride, is a polyamine. Spermidine Trihydrochloride is widely distributed in organisms and is biosynthesized by putrescine (butanediamine) and adenosylmethionine. Spermidine can inhibit neuron synthetase, bind, and precipitate DNA; it can also be used to purify DNA-binding proteins and stimulate T4 polynucleotide kinase activity.

Spermidine trihydrochloride is a polyamine that inhibits neuronal nitric oxide synthase (nNOS) and binds and precipitates DNA. It may be used to purify DNA binding proteins.

On September 1, 2013, German and Austrian scientists collaborated to show that spermidine may prevent Alzheimer’s disease.

spermidine trihydrochloride

Reference:

  1. Cull, M; McHenry, CS (1990). Preparation of extracts from prokaryotes. Methods in Enzymology. 182. pp. 147–53.
  2. Wu, WH; Morris, DR (1973). “Biosynthetic arginine decarboxylase from Escherichia coli. Subunit interactions and the role of magnesium ion”. The Journal of Biological Chemistry. 248 (5): 1696–9.
  3. Tabor, CW; Tabor, H (1984). “Polyamines”. Annual Review of Biochemistry. 53: 749–90.