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  • 040-000-337 Spermidine Trihydrochloride, CAS 334-50-9

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    040-000-337 Spermidine Trihydrochloride, CAS 334-50-9

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    About This Item

    Catalog No.
    040-000-337
    Synonym Spermidine
    Keywords Anti-aging, inhibit neuron synthetase, Alzheimer's disease
    Related products β-Nicotinamide mononucleotide, NMN, Nicotinamide Riboside, NR, Dasatinib Monohydrate

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    Description

    Spermidine Trihydrochloride Specifications


    Product Name Spermidine
    CAS Registry Number 334-50-9
    Molecular Formula C7H19N3
    Molecular Weight 145.2 g/mol
    Purity 99 %
    Appearance White powder
    Shelf life 2 years
    Functions Induce phagocytosis, Retarded protein aging, Inhibition of neuronal NO synthase (nNOS)

    Spermidine Trihydrochloride Description


    Spermidine, also known as Spermidine Trihydrochloride, is a polyamine. Spermidine Trihydrochloride is widely distributed in organisms and is biosynthesized by putrescine (butanediamine) and adenosylmethionine. Spermidine can inhibit neuron synthetase, bind, and precipitate DNA; it can also be used to purify DNA-binding proteins and stimulate T4 polynucleotide kinase activity.

    Spermidine trihydrochloride is a polyamine that inhibits neuronal nitric oxide synthase (nNOS) and binds and precipitates DNA. It may be used to purify DNA binding proteins.

    On September 1, 2013, German and Austrian scientists collaborated to show that spermidine may prevent Alzheimer's disease.

    spermidine trihydrochloride

    Reference:


    1. Cull, M; McHenry, CS (1990). Preparation of extracts from prokaryotes. Methods in Enzymology. 182. pp. 147–53.
    2. Wu, WH; Morris, DR (1973). "Biosynthetic arginine decarboxylase from Escherichia coli. Subunit interactions and the role of magnesium ion". The Journal of Biological Chemistry. 248 (5): 1696–9.
    3. Tabor, CW; Tabor, H (1984). "Polyamines". Annual Review of Biochemistry. 53: 749–90.

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