030-000-257 Nicotinamide Riboside, NR, CAS 1341-23-7

Description

Nicotinamide Riboside Specifications

Nicotinamide Riboside Description

Nicotinamide riboside is a precursor of NAD+ and a source of vitamin B3. It increases the intracellular and mitochondrial NAD+, which could increase the cell viability and help to anti-aging. It also increases cerebral cortex NAD+ and reduces cognitive deterioration in mice models of Alzheimer’s disease. Levels of NAD+ in the liver and skeletal muscle can be increased by Nicotinamide riboside, this makes the body prevents body weight gain in mice fed a high-fat diet.

Nicotinamide Riboside Benefits

Because most of the research on nicotinamide riboside and NAD+ is from animal studies, no conclusive data on their effectiveness in humans can be obtained.

That being said, here are some health benefits that nicotinamide riboside can have on nicotinamide riboside. Nicotinamide riboside increases NAD+ levels and is associated with potential health benefits for aging, brain health, heart disease risk, and more.

• Nicotinamide riboside helps increase NAD+ levels in the body. In response, NAD+ activates several enzymes that can activate normal growth.
• Nicotinamide riboside may help protect brain cells.
  In a test-tube study, nicotinamide riboside increased NAD+ levels and significantly improved mitochondrial function in stem cells of people with Parkinson’s disease (19Trusted Source).
• Nicotinamide riboside may reduce the risk of heart disease.
  In humans, nicotinamide riboside increased NAD+ levels, helped reduce aortic stiffness, and reduced systolic blood pressure in adults at risk for hypertension.
• Other potential benefits:
  Help you lose weight
  It can reduce the risk of cancer
  It can help cure jet lag
  Healthy muscles can promote growth

Nicotinamide Riboside Applications

• Ingredient in nutraceuticals
• Laboratory research

Reference:

1. Shi W, Hegeman M A, Van Dartel D A M, et al. Effects of a wide range of dietary nicotinamide riboside (NR) concentrations on metabolic flexibility and white adipose tissue (WAT) of mice fed a mildly obesogenic diet[J]. Molecular Nutrition & Food Research, 2017:1600878.
2. Nicotinic acid, nicotinamide, and nicotinamide riboside: a molecular evaluation of NAD+ precursor vitamins in human nutrition.Bogan KL, Brenner C Annu Rev Nutr. 2008; 28():115-30.
3. NACARELLI T, LAU L, FUKUMOTO T, et al. NAD+ metabolism governs the proinflammatory senescence-associated secretome[J]. Nature Cell Biology, 2019: 1.