040-000-301 Vincamine, CAS 1617-90-9

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Synonyms Angiopac, Devincan, Equipur, Minorin
Source Vincami-norL
Type Indole alkaloid
Keywords Metabolism, vascular, indole alkaloid, arteriosclerosis
Related products Losartan Potassium, Horny Goat Weed Extract, Timclol Maleate
Description

Description

Vincamine Specifications

Product Name Vincamine
CAS Registry Number 1617-90-9
Molecular Formula C21H26N2O3
Molecular Weight 354.4 g/mol
Purity >99%
Appearance White powder
Package 1kg-25kg
Shelf life 2 years
Functions Treatment of arteriosclerosis, cerebral infarction

Vincamine Description

Vincamine is an indole alkaloid found in the leaves of V. minor and C. roseus that is used as a peripheral vasodilator to increase blood flow to the brain. Vincamine contracts excised human cerebrovascular smooth muscle in vitro with an EC50 value of 30 μM and has been explored as a pharmacotherapy to treat cerebral metabolic and vascular diseases. Stanford Chemicals (SCC) provides customers with high-quality Vincamine at a very competitive price.

Vincamine Applications

Vincamine can be used in the following fields:

  • Treatment of ischemic cerebrovascular disease
  • Laboratory research

Reference:

  1. Young, A.R., Bouloy, M., Boussard, J.F., et al. Direct vascular effects of agents used in the pharmacotherapy of cerebrovascular disease on isolated cerebral vessels. Journal of Cerebral Blood Flow and Metabolism 1(1), 117-128 (1981).
  2. Lim, C.C., and James, I.M. The effect of an acute infusion of vincamine and ethyl apovincaminate on cerebral blood flow in healthy volunteers. British Journal of Clinical Pharmacology 9(1), 100-101 (1980).
  3. Nowicki, J.P., MacKenzie, E.T., and Spinnewyn, B. Effects of agents used in the pharmacotherapy of cerebrovascular disease on the oxygen consumption of isolated cerebral mitochondria. Journal of Cerebral Blood Flow and Metabolism 2(1), 33-40 (1982).