|Synonyms||Angiopac, Devincan, Equipur, Minorin|
|Keywords||Metabolism, vascular, indole alkaloid, arteriosclerosis|
|Related products||Losartan Potassium, Horny Goat Weed Extract, Timclol Maleate|
|CAS Registry Number||1617-90-9|
|Molecular Weight||354.4 g/mol|
|Shelf life||2 years|
|Functions||Treatment of arteriosclerosis, cerebral infarction|
Vincamine is an indole alkaloid found in the leaves of V. minor and C. roseus that is used as a peripheral vasodilator to increase blood flow to the brain. Vincamine contracts excised human cerebrovascular smooth muscle in vitro with an EC50 value of 30 μM and has been explored as a pharmacotherapy to treat cerebral metabolic and vascular diseases. Stanford Chemicals (SCC) provides customers with high-quality Vincamine at a very competitive price.
Vincamine can be used in the following fields:
- Treatment of ischemic cerebrovascular disease
- Laboratory research
- Young, A.R., Bouloy, M., Boussard, J.F., et al. Direct vascular effects of agents used in the pharmacotherapy of cerebrovascular disease on isolated cerebral vessels. Journal of Cerebral Blood Flow and Metabolism 1(1), 117-128 (1981).
- Lim, C.C., and James, I.M. The effect of an acute infusion of vincamine and ethyl apovincaminate on cerebral blood flow in healthy volunteers. British Journal of Clinical Pharmacology 9(1), 100-101 (1980).
- Nowicki, J.P., MacKenzie, E.T., and Spinnewyn, B. Effects of agents used in the pharmacotherapy of cerebrovascular disease on the oxygen consumption of isolated cerebral mitochondria. Journal of Cerebral Blood Flow and Metabolism 2(1), 33-40 (1982).