Vincamine Description

Vincamine is an indole alkaloid found in the leaves of V. minor and C. roseus that is used as a peripheral vasodilator to increase blood flow to the brain. Vincamine contracts excised human cerebrovascular smooth muscle in vitro with an EC50 value of 30 μM and have been explored as a pharmacotherapy to treat cerebral metabolic and vascular diseases. Stanford Chemicals (SCC) provides customers with high-quality Vincamine at a very competitive price.

Vincamine is a monoterpenoid indole alkaloid obtained from the leaves of Vinca minor with a vasodilatory property.

Vincamine Specifications

Product Name	Vincamine
CAS Registry Number	1617-90-9
Molecular Formula	C21H26N2O3
Molecular Weight	354.4 g/mol
Purity	>99%
Appearance	White powder
Package	1kg-25kg
Shelf life	2 years
Functions	Treatment of arteriosclerosis, cerebral infarction

Vincamine Applications

Vincamine can be used in the following fields:

• Treatment of ischemic cerebrovascular disease
• Laboratory research

Reference:

1. Young, A.R., Bouloy, M., Boussard, J.F., et al. Direct vascular effects of agents used in the pharmacotherapy of cerebrovascular disease on isolated cerebral vessels. Journal of Cerebral Blood Flow and Metabolism 1(1), 117-128 (1981).
2. Lim, C.C., and James, I.M. The effect of an acute infusion of vincamine and ethyl apovincaminate on cerebral blood flow in healthy volunteers. British Journal of Clinical Pharmacology 9(1), 100-101 (1980).
3. Nowicki, J.P., MacKenzie, E.T., and Spinnewyn, B. Effects of agents used in the pharmacotherapy of cerebrovascular disease on the oxygen consumption of isolated cerebral mitochondria. Journal of Cerebral Blood Flow and Metabolism 2(1), 33-40 (1982).