1,2,3-tri-O-acetyl-5-deoxy ribofuranose Introduction

1,2,3-tri-O-acetyl-5-deoxy ribofuranose Specification

Chemical Properties:

• Stability: Acetyl groups enhance stability by preventing unwanted oxidation or side reaction with free hydroxyl groups.
• Solubility: Slightly soluble in organic solvents (e.g., dichloromethane, ethyl acetate) but insoluble in water.
• Reactivity: The anomeric (1-position) acetyl group is relatively more reactive, which is favorable for glycosylation or modification.

1,2,3-tri-O-acetyl-5-deoxy ribofuranose Applications

• Synthetic Intermediate: Used in the synthesis of nucleosides, nucleotides, and carbohydrate-derived medicines (e.g., modified antiviral drugs).
• Group Protecting Strategy: Acetyl groups are utilized as transient protecting groups in carbohydrate chemistry and can be removed later in a selective manner.