|Synonyms||Apovincaminic Acid ethyl ester, (3α,16α)-eburnamenine-14-carboxylic acid, ethyl ester|
|Type||Derivative of vinca alkaloid vincamine|
|Source||Voacanga Africana/ vinca minor|
|Related products||Losartan Potassium, Horny Goat Weed Extract, Timclol Maleate|
|CAS Registry Number||42971-09-5|
|Molecular Weight||350.5 g/mol|
|Shelf life||2 years|
|Functions||Treatment of cerebrovascular|
Vinpocetine is a semi-synthetic alkaloid commonly used as an inhibitor of phosphodiesterase 1 (PDE1), blocking the hydrolysis of both cAMP and cGMP. In addition to its use as a selective PDE1 inhibitor in basic research, vinpocetine has diverse cerebral and neurological effects in vivo. Vinpocetine also directly inhibits the kinase activity of IKKβ and blocks TNF-α- and LPS-mediated activation of NF-κB in cells and in vivo. Stanford Chemicals (SCC) provides customers with high-quality vinpocetine at a very competitive price.
Vinpocetine can be used in the following fields:
- Laboratory research
- Treatment of cerebrovascular
- Jeon, K.I., Xu, X., Aizawa, T., et al. Vinpocetine inhibits NF-κB-dependent inflammation via an IKK-dependent but PDE-independent mechanism. Proceedings of the National Academy of Sciences of the United States of America 107(21), 9795-9800 (2016)
- Medina, A.E. Therapeutic utility of phosphodiesterase type I inhibitors in neurological conditions. Front.Neurosci. 5(21), (2011).