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040-000-332 Didesethyl Chloroquine, CAS 4298-14-0

didesethyl chloroquine
SKU: 040-000-332 Category:
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Synonyms N4-(7-Chloro-4-quinolinyl)-1,4-pentanediamine; 4-[(4-Amino-1-methylbutyl)amino]-7-chloroquinoline; Bisdeethylchloroquine; Bisdesethylchloroquine; N,N-Dideethylchloroquine
Keywords COVID-19, Chloroquine
Related products Remdesivir (development code GS-5734); Losartan Potassium, Hydroxychloroquine Sulfate
Description

Description

Didesethyl Chloroquine Specifications

Product Name Didesethyl Chloroquine
CAS Registry Number 4298-14-0
Molecular Formula C14H18ClN3
Molecular Weight 263.77 g/mol
Appearance Brown solid
Package 1kg-25kg
Shelf life 2 years

Didesethyl Chloroquine Description

Didesethyl Chloroquine is the principal metabolite of chloroquine in man, another one is desethylchloroquine. It is a COVID19-related research product.

Desethyl chloroquine is a major desethyl metabolite of Chloroquine. Chloroquine diphosphate is an inhibitor of autophagy and toll-like receptors (TLRs). Desethyl chloroquine possesses antiplasmodic activity.

didesethyl chloroquine

Didesethyl Chloroquine Applications

  • Used in COVID19-related research

Reference:

  1. Ohkuma, S., et al.: J. Cell. Biol., 90, 656 (1981)
  2. Araki, N., et al.: J. Biol. Chem., 267, 10211 (1992)
  3. Projean, D., et al.: Drug Metab. Dispos., 31, 748 (2003)
  4. Traebert, M., et al.: Eur. J. Pharmacol., 484, 41 (2004)
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