|Keywords||metastatic castration-resistant prostate cancer|
|Related products||Red clover extract, Viagra (Sildenafil Citrate) Powder|
Abiraterone Acetate Specifications
|Product Name||Abiraterone Acetate|
|CAS Registry Number||154229-18-2|
|Molecular Weight||391.55 g/mol|
|Shelf life||2 years|
|Functions||Treatment of mCSPC|
Abiraterone Acetate Description:
Abiraterone Acetate is a CYP17 inhibitor, suitable for use in combination with prednisone for the treatment of patients with metastatic castration-refractory prostate cancer who have previously received docetaxel-containing chemotherapy.
Abiraterone Acetate Applications:
Abiraterone Acetate is used in combination with prednisone, a corticosteroid, as a treatment for mCRPC (previously called hormone-resistant or hormone-refractory prostate cancer).
- O’Donnell, A., Judson, I., Dowsett, M., et al. Hormonal impact of the 17α-hydroxylase/C17,20-lyase inhibitor abiraterone acetate (CB7630) in patients with prostate cancer. British Journal of Cancer 90(12), 2317-2325 (2004).
- Ryan, C.J., Smith, M.R., de Bono, J.S., et al. Abiraterone in metastatic prostate cancer without previous chemotherapy. New England Journal of Medicine 368(2), 138-148 (2013).
- Potter, G.A., Barrie, S.E., Jarman, M., et al. Novel steroidal inhibitors of human cytochrome P45017α (17α-hydroxylase-C17,20-lyase): Potential agents for the treatment of prostatic cancer. Journal of Medicinal Chemistry 38(13), 2463-2471 (1995).