040-000-549 Calcium Folinate

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Type Active Pharmaceutical ingredient
CAS No. 1492-18-8
Chemical Formula C20H21CaN7O7
Packaging 25mg, 100mg, 250mg, 1g, 5g, etc.
Form Light Yellow Powder
Assay ≥95%
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Calcium Folinate Introduction

Calcium Folinate is an antidote for folic acid antagonists, yellowish-white to yellow crystals at room temperature, or amorphous powder. Calcium folinate is a reduced formylation derivative of folic acid, and its function is similar to that of folic acid, which is the activated form of folic acid in the body. After entering the human body, it is converted into tetrahydrofolate by tetrahydrofolate reductase, which can effectively resist the toxic reaction caused by methotrexate.

Calcium Folinate can “rescue” the toxic reaction of excessive folic acid antagonists in the body, which is beneficial to the synthesis of thymine nucleotides, DNA, RNA, and even protein, and can stimulate the growth and maturation of white blood cells.

Calcium Folinate Specification

Melting Point >300℃
Form Light Yellow Powder
Packaging 25mg, 100mg, 250mg, 1g, 5g, etc.


Calcium Folinate Applications

Calcium Folinate is used to relieve the toxic reactions caused by an overdose of aminopterin and methotrexate, and it can also be used to treat giant red blood cell anemia.