Citrates

Citrates are extensively used in food and beverages due to their remarkably wide range of applications. Depending on the form, they can function as buffers, chelating agents, preservatives, or flavoring agents.

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Typical Citrates

1. Sodium Citrate: It possesses good pH buffering capacity, metal ion chelating ability, and safety.
2. Calcium Citrate: An important calcium nutritional fortifier and functional additive.
3. Ferric Ammonium Citrate: Primarily used for iron fortification in food, such as in preventing iron deficiency anemia.
4. Potassium Citrate: This salt is a good source of potassium.
5. Magnesium Citrate: Mainly used as an osmotic laxative for bowel cleansing.
6. Zinc Citrate: An important source of zinc.
7. Citric Acid: Primarily used as a natural preservative, acidulant, pH regulator, metal cleaner, and intermediate in cosmetics and chemical industries.

Core Functions

Despite their variety, the core functions of citrates can be summarized as follows, which also form the basis for their widespread application:

1. Excellent Chelating Agent: Capable of strongly binding metal ions (such as calcium, magnesium, iron), which is crucial in water softening, preventing food oxidation and discoloration, medical anticoagulation, and treating mineral deficiencies.

2. Safe pH Buffer: Stabilizes the acidity or alkalinity of a system and is widely used in food, pharmaceuticals, and cosmetics.

3. High Biocompatibility and Safety: Most citrates are generally recognized as safe for use in food and medicine.

4. Provider of Essential Nutrients: Serves as an excellent carrier and supplemental form of mineral elements such as calcium, iron, potassium, zinc, and magnesium.

Therefore, from our daily food and beverages, health products, and pharmaceuticals to household cleaning and industrial production, citrates play an indispensable role.

FAQ

What is the difference between sodium citrate and citric acid?

Citric acid is an organic acid primarily used to provide sourness and functions as a preservative and chelating agent. Sodium citrate is the neutralized product of citric acid and sodium. It is less acidic and more suitable as a buffer, emulsifier, or anticoagulant.

Are citrates safe?

Most citrates are recognized as safe by international food regulations (e.g., FDA, EFSA) and can be used in food, pharmaceuticals, and cosmetics within standard limits. However, excessive intake of certain citrates (e.g., magnesium citrate) may cause diarrhea or electrolyte imbalances.

What are the uses of citrates in the pharmaceutical field?

Anticoagulation: Sodium citrate is used to prevent blood clotting during blood transfusions.

Mineral supplementation: Calcium citrate, ferric citrate, etc., are used to prevent or treat deficiencies.

Pharmaceutical excipients: Serve as pH adjusters or stabilizers.

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