040-000-313 Florfenicol CAS 73231-34-2

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Synonyms 2,2-dichloro-N-[(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]-acetamide
Keywords Antibiotic, intestinal infections
Related products Ritonavir,  Arbidol Hydrochloride, Sulfadiazine
Description

Description

Florfenicol Specifications

Product Name Florfenicol
CAS Registry Number 73231-34-2
Molecular Formula C12H14Cl2FNO4S
Molecular Weight 358.2 g/mol
Purity >99 %
Appearance White powder
Package 1kg-25kg
Shelf life 2 years
Functions Antibiotic

Florfenicol Description

Florfenicol is a monofluoro derivative of thiamphenicol, a white or off-white crystalline powder, odorless. Florfenicol is slightly soluble in water and chloroform, slightly soluble in glacial acetic acid, and soluble in methanol and ethanol. It is a new broad-spectrum antibacterial drug for veterinary medicine developed successfully in the late 1980s.

Florfenicol is a broad-spectrum bacteriocidal antibiotic that acts against the 50S ribosome of bacteria.

Florfenicol Applications

Florfenicol is a special antibacterial drug for animals, used for bacterial diseases of pigs, chickens, and fish caused by sensitive bacteria, especially for respiratory infections and intestinal infections.

Florfenicol is a broad-spectrum antibiotic used to treat infections in aquaculture species as well as a number of livestock species, including bovine, and porcine.

Reference:

  1. Neu, H.C., and Fu, K.P. In vitro activity of chloramphenicol and thiamphenicol analogs. Antimicrob. Agents Chemother. 18(2), 311-316 (1980).
  2. Cannon, M., Harford, S., and Davies, J. A comparative study on the inhibitory actions of chloramphenicol, thiamphenicol, and some fluorinated derivatives. J. Antimicrob. Chemother. 26(3), 307-317 (1990).
  3. Priebe, S., and Schwarz, S. In vitro activities of florfenicol against bovine and porcine respiratory tract pathogens. Antimicrob. Agents Chemother. 47(8), 2703-2705 (2003).