HA6993 Kava Extract Powder

Description

Kava Extract Powder Description

Kava Extract Powder is a pale-yellow to brown, fine, hygroscopic powder with a characteristic pungent, earthy odor obtained from the roots of Piper methysticum that have been dried. It contains as its main bioactive constituents kavalactones like kavain, dihydrokavain, methysticin, and yangonin, typically standardized to 30%–80% content. The lipophilic compounds are poorly soluble in water but highly miscible in organic solvents like ethanol or glycerin. Chemically, kavalactones modulate gamma-aminobutyric acid (GABA-A) receptor activity and block monoamine oxidase B (MAO-B), potentiating neuronal hyperpolarization to induce muscle relaxation and anxiolysis without affecting cognitive function.

The extract has thermolability with degradation occurring above 60°C, and should be shielded from light and oxygen to protect against oxidation of unsaturated lactone rings. Analytical profiles determine trace flavonoids and chalcones that increase kavalactone bioavailability by pharmacokinetic synergies. Stability demands storage under <25°C in desiccant-packed airtight containers to prevent moisture uptake and clumping. Lead ≤20 ppm heavy metal residues and microbial contamination meet pharmacopeial requirements, while residual solvent levels are controlled for food-grade safety levels. Despite effectiveness, hepatotoxicity potential due to pyrone derivatives means purity certification using HPLC must be carefully performed to exclude adulterants.

Kava Extract Powder Specifications

Properties

*The above product information is based on theoretical data. For specific requirements and detailed inquiries, please contact us.

Kava Extract Powder Uses

• Nutraceuticals and Dietary Supplements: Kava Extract Powder is tabletted, encapsulated, and tinctured for sleep and anxiety relief. Its kavalactones are GABA-A receptor binders that lead to relaxation with no next-day drowsiness and are a non-prescription alternative to benzodiazepines in the treatment of mild stress-induced insomnia. Efficacy has been verified in clinical trials at 50–300 mg per day for mild-to-moderate anxiety disorders.
• Functional Foods and Soft Drinks: Formulated into alcohol-free tonics, tea, and sparkling drinks as a social stress-relief friend. The earthy flavor of kava is masked with citrus or ginger in ready-to-drink beverages sold to sober-curious individuals. Synergistic combinations with adaptogens like ashwagandha build stress-resistance in functional elixirs.
• Pharmaceuticals and Clinical Therapeutics: Developed in anxiolytic and muscle-relaxant medications for the treatment of generalized anxiety disorder (GAD) and tension headaches. Standardized extract (≥70% kavalactones) is enteric-coated to be resistant to gastric degradation and enhance bioavailability for longer neurological activity.
• Cosmetics and Topical Products: Incorporated into calming creams and serums for their anti-inflammatory benefits. Kavalactones inhibit TNF-α and COX-2 signaling, soothing redness and sensitivity in reactive skin, as antioxidants remove oxidative stress from environmental aggressors.
• Research and Development: Studied neuroprotective mechanisms against excitotoxicity and mitochondrial damage. Future applications explore kavain’s potential in addiction treatment protocols through modulating dopamine reward pathways.

Kava Extract Powder FAQs

Q1. Will this help my acute work meeting anxiety?
Yes. Take 100–200 mg 30 minutes prior. Kavalactones induce calm focus within 20–40 minutes by enhancing GABA function—ideal for high-pressure environments without sedation.
Q2. Is it safe with my antidepressant (SSRI)?
Avoid combination. Kava can increase serotonin effects, creating “serotonin syndrome.” Always consult your prescriber before combining with SSRIs/SNRIs.
Q3. How is it different from valerian root?
Valerian induces sleep but drowsiness; kava can alleviate anxiety without loss of alertness. Use the two together for synergistic sleep initiation and maintenance.