Hypericin Powder Description

Hypericin Powder is a crystalline solid ranging in color from deep red to purple, accompanied by a subtle aromatic scent. It has a molecular weight of 504.45 g/mol and decomposes within the temperature range of 320–325°C. In alcohol-based solutions, the compound shows strong absorbance peaks at 545 nm and 590 nm. While it is insoluble in water, it demonstrates high solubility in dimethyl sulfoxide (DMSO), reaching concentrations up to 50 mg/mL. When excited at 590 nm, the powder emits fluorescence at 595 nm. Under an inert atmosphere and stored in amber glass vials at -20°C, it maintains stability for up to 36 months. However, extended UV light exposure or temperatures exceeding 50°C will lead to degradation. With a logP value of 5.2, the substance is highly lipophilic. Quality testing indicates undetectable heavy metals (Pb < 0.1 ppm, Cd < 0.05 ppm) and minimal microbial content (total count < 100 CFU/g).

Hypericin Powder Specifications

Properties

*The above product information is based on theoretical data. For specific requirements and detailed inquiries, please contact us.

Hypericin Powder Benefits and Uses

• Photodynamic Therapy: Used in cancer treatment to selectively eliminate malignant cells upon activation with visible light.
• Antiviral Studies: Evaluated for efficacy against enveloped viruses such as herpes and hepatitis in experimental therapeutics.
• Neuropharmacology: Studied for its influence on neurotransmitter activity in models of depression and anxiety.
• Dermatological Use: Incorporated into topical treatments for conditions including psoriasis and vitiligo, combined with controlled light application.
• Bio-imaging: Serves as a fluorescent tracer in cellular imaging and distribution studies.

People Also Ask

Q1: How quickly does hypericin degrade under ambient light?
Substantial decomposition occurs within 2–4 hours; it is essential to handle the material under red light or in total darkness.

Q2: Why is DMSO the preferred solvent over ethanol?
DMSO provides superior solubility (50 mg/mL vs. 20 mg/mL in ethanol) and improves delivery into cells.

Q3: Why does the powder appear black instead of red?
The dark hue results from high-purity crystalline aggregation. Dissolving in DMSO should yield a red fluorescent solution—absence of fluorescence suggests degradation.