050-000-258 Physcion, CAS 521-61-9

Description

Specifications of Physcion

Description of Physcion

Physcion is an anthraquinone isolated from rheum officinale, and has antitumor and antifungal activity. Experiments have shown that it has a strong inhibitory effect on the growth of human cervical cancer Hela cells. Physcion has good systemic conduction, inhibits the formation of fungal hyphae, sputum, and spores by interfering with the biosynthesis of chitin in the cell wall of pathogenic fungi, and blocking the spread of disease. It has low toxicity to humans and animals, is environmentally friendly, and is suitable for the production of green and organic vegetables as a pesticide.

Benefits of Physcion

• Antiproliferative Effects: Physcion has been identified with anticancer properties. It principally causes the induction of programmed cell death, inhibition of proliferation of cells, and reduction in the growth of tumors. This compound is a candidate for research into cancer therapies targeting various signal pathways.
• Anti-inflammatory Effects: It has also been noted that physcion exhibits anti-inflammatory activity through the inhibition of inflammatory mediators such as cytokines and inhibition of the activity of inflammation-linked enzymes like COX-2.
• Antioxidant Activity: Physcion has shown antioxidant activity in terms of scavenging free radicals and protecting against oxidative stress in cells. Such an attribute finds application in the prevention or mitigation of oxidative damage associated with a variety of chronic diseases, such as cardiovascular diseases and neurodegenerative disorders.
• Antiviral Activity: There are limited reports that physcion may exert antiviral activity, especially against the influenza virus and hepatitis B virus. It interferes with the replication cycle of viruses and viral enzyme activity.
• Pesticidal Properties: Physcion has its usages in application as a natural pesticide. The antifungal properties of this compound make it useful in plant pathogen control and, therefore, a very viable organic alternative to synthetic pesticides in agriculture.
• Laxative Effect: Like other anthraquinones, physcion has a laxative effect through the stimulation of bowel movements. This property is usually utilized in folk medicine for treating constipation.
• Hepatoprotective Effects: Physcion has been studied with respect to its protective effects on the liver. It can help reduce liver inflammation and prevent any damage from toxins and may be useful in the treatment of liver diseases.

Applications of Physcion

• As pesticide
• Studies of antibiotics, antifungals, bioactive small molecules, and cell biology.