040-000-400 3-(4-Chlorobutyl)indole-5-carbonitrile

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Category Pharmaceutical raw materials
Synonym 3-(4-Chlorobutyl)-5-cyanoindole, 3-(4-Chlorbutyl)-1H-indol-5-carbonitril
CAS No. 143612-79-7
Chemical Formula C13H13ClN2
Molecular Weight 232.71
Appearance White Powder
Package Customized Package.
Grade Medicine grade
Assay >97%


3-(4-Chlorobutyl)indole-5-carbonitrile Introduction

3-(4-Chlorobutyl)indole-5-carbonitrile is used to synthesize vilazodone, which is a medicine that cures depression.

Depression is a common mental illness. Its clinical symptoms are low mood, restless sleep, slow thinking, loss of interest, and loss of appetite. The cause of depression is not yet fully understood. It is generally believed that it is caused by two factors, psychological and biological (including neurotransmitter etiology and genetic etiology, etc.). The different pathogenesis of depression also determines the different treatment methods.

Generally speaking, it can be divided into two categories: drug therapy and non-drug therapy. Symptoms caused by psychological problems can be relieved by a variety of non-pharmacological methods such as physical therapy, behavioral therapy, and art therapy. Depression caused by neurotransmitter disorders or genetic factors needs to be treated with corresponding drugs.


3-(4-Chlorobutyl)indole-5-carbonitrile Applications

3-(4-Chlorobutyl)-5-cyanoindole is a key intermediate in the synthesis of vilazodone. It is mainly used to synthesize vilazodone, such as 3-(4-chlorobutyl)-1H-indole.

3-(4-Chlorobutyl)indole-5-carbonitrile Specification

Appearance White to Almost white powder to crystal
Purity(GC) min. 97.0 %
Melting point 98.0 to 102.0 °C
Melting Point 100 °C
Solubility (soluble in) Dimethylformamide


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