Ademetionine Disulfate Tosylate

Product Name: Ademetionine Disulfate Tosylate (SAMe)
Synonyms: SAM-T; fo-1561; SAME-PTS; Ademetionine disulfate; ADEMETHIONINE SULFATE TOSYLATE; Ademetionine disulfate tosylate; AdeMethionine Disulfate Tosylate;
CAS #: 97540-22-2
Molecular Formula: C15H22N6O5S.2(H2SO4).C7H8SO3

Molecular Weight: 294.31

Description

Description

Product Name: Ademetionine Disulfate Tosylate (SAMe)
Synonyms: SAM-T; fo-1561; SAME-PTS; Ademetionine disulfate; ADEMETHIONINE SULFATE TOSYLATE; Ademetionine disulfate tosylate; AdeMethionine Disulfate Tosylate;
CAS #: 97540-22-2
Molecular Formula: C15H22N6O5S.2(H2SO4).C7H8SO3

Molecular Weight: 294.31

 Ademetionine Disulfate Tosylate

Application

The therapy of depression, arthritis, chronic hepatitis and cholestasia; moreover, it can be used in the prevention of liver cancer, or relieve the poisoning of chemicals, alcohol and cancer to the liver, improve the curing of wound and growth of cartilage tissue; it also can adjust the function of nerve centre system.

 Ademetionine Disulfate Tosylate

 

TEST ITEM STANDARD
Appearance White or off-white powder
Identification by HPLC The retention time of the major peak in the chromatogram of the assay preparation corresponds to that in the chromatogram of ademetionine in the system suitability solution as obtained in the assay
Identification by IR Consistent with the spectrum obtained with the reference standard
Water(K.F.) ≤3.0%
Solubility Soluble in water
TSFA by HPLC 21.7-23.5%
content of sulfate by IC 23.5-26.5%
SAME ion Assay by HPLC 50%-53%
Assay BY HPLC ≥95%
Isomeric ratio by HPLC S,S-isomer≥60%
PH 1.0-2.0
Related compounds by HPLC Adenine≤0.7%
Methyltioadenosin≤0.7%
Adenosine ≤0.5%
S-adenosyl-homocysteine ≤0.7%
Residue on ignition ≤0.5%
Heavy metals ≤20ppm
TEST ITEM STANDARD