040-000-181 Ademetionine Disulfate Tosylate
Product Name: Ademetionine Disulfate Tosylate (SAMe)
Synonyms: SAM-T; fo-1561; SAME-PTS; Ademetionine disulfate; ADEMETHIONINE SULFATE TOSYLATE; Ademetionine disulfate tosylate; AdeMethionine Disulfate Tosylate;
CAS #: 97540-22-2
Molecular Formula: C15H22N6O5S.2(H2SO4).C7H8SO3
Molecular Weight: 294.31
Description
Ademetionine Disulfate Tosylate Description
Ademetionine Disulfate Tosylate is the disulfate–tosylate mixed salt of a mixture of diastereoisomers of the ademetionine ions.
Product Name: Ademetionine Disulfate Tosylate (SAMe)
Synonyms: SAM-T; fo-1561; SAME-PTS; Ademetionine disulfate; ADEMETHIONINE SULFATE TOSYLATE; Ademetionine disulfate tosylate; AdeMethionine Disulfate Tosylate;
CAS #: 97540-22-2
Molecular Formula: C15H22N6O5S.2(H2SO4).C7H8SO3
Molecular Weight: 294.31
Ademetionine Disulfate Tosylate Application
The therapy of depression, arthritis, chronic hepatitis, and cholestasia; moreover, it can be used in the prevention of liver cancer, or relieve the poisoning of chemicals, alcohol, and cancer to the liver, improve the curing of wound and growth of cartilage tissue; it also can adjust the function of nerve center system.
Ademetionine Disulfate Tosylate Specification
| TEST ITEM | STANDARD |
| Appearance | White or off-white powder |
| Identification by HPLC | The retention time of the major peak in the chromatogram of the assay preparation corresponds to that in the chromatogram of ademetionine in the system suitability solution as obtained in the assay |
| Identification by IR | Consistent with the spectrum obtained with the reference standard |
| Water(K.F.) | ≤3.0% |
| Solubility | Soluble in water |
| TSFA by HPLC | 21.7-23.5% |
| content of sulfate by IC | 23.5-26.5% |
| SAME ion Assay by HPLC | 50%-53% |
| Assay BY HPLC | ≥95% |
| Isomeric ratio by HPLC | S,S-isomer≥60% |
| PH | 1.0-2.0 |
| Related compounds by HPLC | Adenine≤0.7% Methyltioadenosin≤0.7% Adenosine ≤0.5% S-adenosyl-homocysteine ≤0.7% |
| Residue on ignition | ≤0.5% |
| Heavy metals | ≤20ppm |
| TEST ITEM | STANDARD |
