Naringin Introduction

Naringin is the major flavonoid glycoside in grapefruit and gives grapefruit juice its bitter taste. It is metabolized to the flavanone naringenin in humans. Both naringin and hesperetin, which are the aglycones of naringin and hesperidin, occur naturally in citrus fruits. Naringin exerts a variety of pharmacological effects such as antioxidant activity, blood lipid-lowering, anticancer activity, and inhibition of selected drug-metabolizing cytochrome P450 enzymes, including CYP3A4 and CYP1A2, which may result in drug-drug interactions in vivo. Ingestion of naringin and related flavonoids can also affect the intestinal absorption of certain drugs, leading to either an increase or decrease in circulating drug levels.

Naringin Functions

1.Inhibition of Aldose reductase.

2.Anti-inflammatory and analgesic effects.

3.It also has antibacterial, antiviral, and antifungal properties.

4.Treatment for candidiasis, earache, throat infections, and diarrhea.

Naringin Application

1. Applied in the food field, various foods are using it as raw materials. 2. Applied in the cosmetic field, it can be used to nourish the skin. 3. Applied in the pharmaceutical field, it is made into a tablet or capsule, which is often used for eat less and coughing much sputum.

 

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