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  • (Discontinued) 040-000-530 Sacubitril Sodium

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    (Discontinued) 040-000-530 Sacubitril Sodium

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    About This Item

    Catalog No.
    040-000-530

    Discontinued

    Type Active Pharmaceutical ingredient
    Synonym AHU377
    CAS No. 149690-05-1
    Chemical Formula C24H28NNaO5
    Appearance white powder
    Packaging 200mg, 500mg, 1g, 5g, 10g
    Assay ≥98%
    Related Products Valsartan, Irbesartan, Olmesartan Medoxomil

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    kg
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    Description

    Sacubitril Sodium Introduction


    Sacubitril Sodium, also known as AHU377, is an angiotensin receptor neprilysin inhibitor being studied for use in combination with valsartan for heart failure. Sacubitril is a prodrug that is activated to LBQ657 by de-ethylation via esterases. LBQ657 inhibits the enzyme neprilysin, which is responsible for the degradation of atrial and brain natriuretic peptides, two blood pressure lowering peptides that work mainly by reducing blood volume.

    Sacubitril Sodium Specification

     

    Appearance white powder
    Melting Point 163-165℃
    Content 99.0%
    Packaging 200mg, 500mg, 1g, 5g, 10g


     

    Sacubitril Sodium Applications


    Sacubitril Sodium, also known as AHU377, is an angiotensin receptor neprilysin inhibitor being studied for use in combination with valsartan for heart failure.

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