Valsartan Introduction

Valsartan is a specific angiotensin II (AT1) receptor antagonist, and it is another non-skin AT1 receptor antagonist used in clinic after losartan. It can regulate systemic blood pressure and maintain electrolyte and body fluids.

It selectively acts on the AT1 receptor subtype and blocks the binding of Ang II to the AT1 receptor, thereby inhibiting vasoconstriction and the release of aldosterone, resulting in a hypotensive effect, but does not inhibit the release of aldosterone caused by potassium ions (K+).

The antihypertensive effect is better than that of enalapril, and it is suitable for the treatment of anti-hypertension, mild to moderate primary hypertension, especially secondary hypertension caused by kidney damage, which can significantly reduce the high blood pressure associated with diabetes or normal renal function. Proteinuria in patients with blood pressure, and has the renal protective effect of promoting the excretion of uric acid and urinary sodium.

The drug is also indicated to reduce cardiovascular mortality in high-risk patients after a heart attack.

Valsartan Specification

Appearance	white powder
Melting Point	116-117℃
Boiling Point	684.9±65.0℃
Density	1.212±0.06 g/cm3
Storage Condition	2-8℃
Content	98.0%
Packaging	1g, 5g

 

Valsartan Applications

The antihypertensive effect of Valsartan is better than that of enalapril, and it is suitable for the treatment of anti-hypertension, mild to moderate primary hypertension, especially secondary hypertension caused by kidney damage, which can significantly reduce the high blood pressure associated with diabetes or normal renal function.