Zinc L-carnosine (CAS: 107667-60-7) Description

Zinc L-carnosine (CAS: 107667-60-7), also called polaprezinc known as PepZin GI™, is a mucosal protective chelated compound that contains L-carnosine and zinc. It is a quadridentate 1:1 complex of a polymeric nature. Although Zinc-L-carnosine contains 23% zinc and 77% L-carnosine by mass, zinc carnosine is a molecule and not a mixture of zinc and L-carnosine. It is a relatively new molecule and has been associated with multiple health benefits.

Zinc L-carnosine is a pharmaceutical compound with direct mucosal cytoprotective and anti-inflammatory action through its antioxidative effects, cytokine modulation and membrane-stabilizing properties.

Zinc L-carnosine (CAS: 107667-60-7) Specifications

Zinc L-carnosine (CAS: 107667-60-7) Applications：

1) Anti-acid effects

2) Anti-inflammatory actions (NFkB, HIF-1)

3) Gastric mucous membrane adhesion

4) Stabilisation of gastric and intestinal mucous membrane

5) Improvement of taste disorders

6) Cellular protection

7) Accelerated wound healing (including pressure sores from oral dosing, and ulcerative colitis from rectal administration)

8) Prevention of chemotherapy-induced oral mucositis

9) Enhances interferon therapy in Hepatitis C

10) The use of zinc carnosine in many oral, gastric, liver, and lower intestinal disorders, as well as an oral treatment of pressure sores, gives practitioners a safe and effective option for either stand-alone or safe adjunct therapy to pharmacological treatment.

There are several studies that support Zinc L-carnosine’s benefits in restoring the gastric lining, healing other parts of the gastrointestinal (GI) tract, improving taste disorders, improving GI disorders, and enhancing skin and liver. Evidence supports the safety and efficacy of Zinc-L-carnosine for the maintenance, prevention, and treatment of the mucosal lining and other epithelial tissues. The research supports its use for gastric ulcers (approved in Japan) and conditions of the upper GI and suggests other applications, particularly for oral mucositis.[1]

  Reference

Susan Hewlings, Douglas Kalman: A Review of Zinc-L-Carnosine and Its Positive Effects on Oral Mucositis, Taste Disorders, and Gastrointestinal Disorders. doi: 10.3390/nu12030665

[1] Susan Hewlings, Douglas Kalman: A Review of Zinc-L-Carnosine and Its Positive Effects on Oral Mucositis, Taste Disorders, and Gastrointestinal Disorders. doi: 10.3390/nu12030665