2-(2-Hydroxyphenyl)-4H-1,3-benzoxazin-4-one Introduction:

2-(2-Hydroxyphenyl)-4H-1,3-benzoxazin-4-one is used to synthesize deferasirox, which has good safety and tolerability, and can significantly reduce the iron load of the heart and liver, and is easy to be accepted by patients. At the same time, deferasirox also has anti-fungal (such as mucor which grows in an iron-rich environment), anti-cell proliferation, anti-malaria, anti-oxidative stress damage, anti-cytotoxicity-induced apoptosis, and other pharmacological properties; it can be used for secondary treatment of hemochromatosis, delayed skin porphyria and other diseases.

2-(2-Hydroxyphenyl)-4H-1,3-benzoxazin-4-one Application:

2-(2-Hydroxyphenyl)-4H-1,3-benzoxazin-4-one is used to synthesize deferasirox, which has good safety and tolerability, and can significantly reduce the iron load of the heart and liver, and is easy to be accepted by patients.

DFS(Deferasirox) can be used to:

• treat reversible renal insufficiency caused by Fanconi syndrome.
• For the treatment of secondary hemochromatosis.
• It can be used to treat delayed skin porphyria.
• For the treatment of myelodysplastic syndrome.
• For the treatment of iron overload caused by blood transfusion in patients with chronic anemia of 2 years and older.

2-(2-Hydroxyphenyl)-4H-1,3-benzoxazin-4-one Specifications

Appearance	White to Orange to Green powder to crystal
Purity(GC)	min. 98.0 %
Melting point	204.0 to 208.0 °C

Melting Point	206 °C
Maximum Absorption Wavelength	371(H2O) nm

 

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