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040-000-403 4-[(4-Methyl-1-piperazinyl)methyl]benzoic Acid Dihydrochloride

4-[(4-Methyl-1-piperazinyl)methyl]benzoic Acid Dihydrochloride
SKU: 040-000-403 Category:
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Category Pharmaceutical raw materials
Synonym 4-(4-Methylpiperazinomethyl)benzoic acid, dihydrochloride
CAS No. 106261-49-8
Chemical Formula C13H20Cl2N2O2
Appearance White to off-white crystalline powder
Package Customized Package.
Packaging DRUM, Plastic Container
Grade Cosmetic grade
Assay ≥98%
Description

Description

4-[(4-Methyl-1-piperazinyl)methyl]benzoic Acid Dihydrochloride Introduction:

4-[(4-Methyl-1-piperazinyl)methyl]benzoic Acid Dihydrochloride is an intermediate of the anti-tumor drug imatinib. Imatinib is an oral drug used to treat the blast phase, accelerated phase, and chronic phase after failure of interferon treatment in adult patients with Philadelphia chromosome (Ber-Abl) positive chronic myelogenous leukemia (CML).

CML is a hematopoietic stem cell disease caused by abnormal DNA of stem cells in the bone marrow. Abnormal DNA will produce abnormal proteins, which interfere with the normal production of white blood cells in the bone marrow, and ultimately lead to a sharp increase in the number of white blood cells. Imatinib is also effective in the treatment of gastrointestinal stromal tumors, with an effective rate of about 50%.

4-[(4-Methyl-1-piperazinyl)methyl]benzoic Acid Dihydrochloride Application:

4-[(4-Methyl-1-piperazinyl)methyl]benzoic Acid Dihydrochloride is an intermediate of the anti-tumor drug imatinib.

4-[(4-Methyl-1-piperazinyl)methyl]benzoic Acid Dihydrochloride Specification

Color White
Quantity Customized
Formula Weight 307.22
Physical Form Crystal-Powder at 20°C
Percent Purity ≥98.0% (HPLC)
Chemical Name or Material 4-[(4-Methyl-1-piperazinyl)methyl]benzoic Acid Dihydrochloride

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