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  • 040-000-403 4-[(4-Methyl-1-piperazinyl)methyl]benzoic Acid Dihydrochloride

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    040-000-403 4-[(4-Methyl-1-piperazinyl)methyl]benzoic Acid Dihydrochloride

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    About This Item

    Catalog No.
    040-000-403
    Category Pharmaceutical raw materials
    Synonym 4-(4-Methylpiperazinomethyl)benzoic acid, dihydrochloride
    CAS No. 106261-49-8
    Chemical Formula C13H20Cl2N2O2
    Appearance White to off-white crystalline powder
    Package Customized Package.
    Packaging DRUM, Plastic Container
    Grade Cosmetic grade
    Assay ≥98%

    Quantity

    kg
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    Description

    4-[(4-Methyl-1-piperazinyl)methyl]benzoic Acid Dihydrochloride Introduction:


    4-[(4-Methyl-1-piperazinyl)methyl]benzoic Acid Dihydrochloride is an intermediate of the anti-tumor drug imatinib. Imatinib is an oral drug used to treat the blast phase, accelerated phase, and chronic phase after failure of interferon treatment in adult patients with Philadelphia chromosome (Ber-Abl) positive chronic myelogenous leukemia (CML).

    CML is a hematopoietic stem cell disease caused by abnormal DNA of stem cells in the bone marrow. Abnormal DNA will produce abnormal proteins, which interfere with the normal production of white blood cells in the bone marrow, and ultimately lead to a sharp increase in the number of white blood cells. Imatinib is also effective in the treatment of gastrointestinal stromal tumors, with an effective rate of about 50%.

    4-[(4-Methyl-1-piperazinyl)methyl]benzoic Acid Dihydrochloride Application:


    4-[(4-Methyl-1-piperazinyl)methyl]benzoic Acid Dihydrochloride is an intermediate of the anti-tumor drug imatinib.

    4-[(4-Methyl-1-piperazinyl)methyl]benzoic Acid Dihydrochloride Specification


    Color White
    Quantity Customized
    Formula Weight 307.22
    Physical Form Crystal-Powder at 20°C
    Percent Purity ≥98.0% (HPLC)
    Chemical Name or Material 4-[(4-Methyl-1-piperazinyl)methyl]benzoic Acid Dihydrochloride

    Related products: Wogonin, Evodiamine, Dasatinib Monohydrate

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