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6 Applications of Matrine

Clinical medicine

1. Diuresis

Bitter sophora root, as a medicinal plant, has the functions of clearing heat, diuresis, insecticide, dispelling dampness, and so on. It also has the functions of anti-virus, anti-tumor, and anti-allergy.

2. Antipathogenic effect

In the test tube, high concentration (1:100) inhibited Mycobacterium tuberculosis. Decoction (8%) had different inhibitory effects on some common skin fungi in vitro.

3. Anti-hepatitis B and C virus effects of oxymatrine

Oxymatrine has shown strong antiviral activity against HBV in vitro and in animal models. It also has an anti-HBV effect on the human body. Many reports have been reported for the treatment of chronic viral hepatitis.

4. Other Roles

Matrine injection into rabbits: found paralysis of the central nervous system, congenital spasm, and eventually died of respiratory arrest. Injection into frogs: initial excitement, then paralysis, slow and irregular breathing, eventually spasm, so that breathing stopped and died. The spasm was caused by spinal reflex.

Beauty and Skin Care

Bitter sophora root can balance oil, astringe pore, remove impurities of the skin, promote the repair of learning to drive nerve cells, make skin more slippery, and have the function of beauty and skincare.

Anti-inflammatory effect

Matrine can inhibit auricle swelling induced by croton oil, abdominal exudation induced by acetic acid and carrageenan pad swelling induced by carrageenan in rats.

Neuroleptic effect

Bitter sophora root has a stabilizing effect. It has a slight analgesic effect when used alone. The combination of threshold dose morphine and Sophora flavescens can increase the analgesic effect.

Antiallergic effect

Matrine can reduce the release of allergic mediators and has an anti-allergic effect.

Agricultural applications

Matrine pesticides used in agriculture actually refer to all the substances extracted from Sophora flavescens, called the extract of bitter sophora root or the total alkaloids of Sophora flavescens. It is widely used in agriculture and has a good control effect. It is a kind of low toxicity, low residue, and environmental protection pesticide. It mainly controls all kinds of pine caterpillar, tea caterpillar, cabbage caterpillar, and other pests. It has many functions, such as insecticidal activity, bactericidal activity, regulating plant growth, and so on.