040-000-278 Alfa-Lipoic Acid, CAS 1077-28-7

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Synonyms 1,2-Dithiolane-3-pentanoic acid, 6,8-Dithiooctanoic acid, DL-α-Lipoic acid, DL-6,8-Thioctic acid
Keywords Anti-oxidation, herbal supplement, weight loss, headaches
Related products  Biotin,  Metformin (Hydrochloride), Retinoic Acid, Stearyl Glycyrrhetinate


Specifications of Alfa-Lipoic Acid

Product Name Alfa-lipoic acid
CAS Registry Number 1077-28-7
Molecular Formula C8H14O2S2
Molecular Weight 206.33
Purity 98.0 %
Melting point 62 °C
Appearance Pale- yellow powder
Solubility Soluble in ethanol or methanol
Shelf life 2 years
Storage Easy to decompose at the light, should be sealed and protected from light
Functions Reduce blood glucose, treat weight loss, treat diabetic nerve pain, regulate NF-κB signal transduction

Description of Alfa-Lipoic Acid

Alpha-lipoic acid is an antioxidant also known as Acetate Replacing Factor, ALA, Biletan, Lipoicin, Thioctan, and many other names.

Alpha-lipoic acid is a naturally occurring fatty acid that can be found in many foods such as yeast, spinach, broccoli, potatoes, and organ meats such as liver or kidney.

Alpha-lipoic acid is an antioxidant that is made naturally in the body and is also found in foods. It is used to break down carbohydrates and to make energy.

alfa lipoic acid

Applications of Alfa-Lipoic Acid

  • Food additives
  • Cosmetic raw material
  • Active pharmaceutical ingredients


  1. Component co-expression and purification of recombinant human pyruvate dehydrogenase complex from baculovirus infected SF9 cells Jiang Y, et al. Protein Expression and Purification 97, 9-16, (2014)
  2. Ameliorative role of antioxidant supplementation on sodium-arsenite induced adverse effects on the developing rat cerebellum Kaushal P, et al. Journal of Ayurveda and integrative medicine , -, (2019)
  3. Oral treatment with alpha-lipoic acid improves symptomatic diabetic polyneuropathy: the SYDNEY 2 trial Ziegler D, et al. Diabetes Care 29(11), 2365-2370, (2006)
  4. Antioxidant and prooxidant activities of alpha-lipoic acid and dihydrolipoic acid Moini H, et al. Toxicology and Applied Pharmacology 182(1), 84-90, (2002)