Epidermal Growth Factor Specifications

Epidermal Growth Factor Description

Epidermal Growth Factor (EGF) is the earliest discovered growth factor and plays an important role in regulating cell growth, proliferation, and differentiation.

Studies have found that EGF has the effect of resurrecting cells in vivo or in vitro. Applying EGF to the skin can simultaneously act on keratinocytes, fibroblasts, smooth cells, and endothelial cells. It can promote cell growth and proliferation, and accelerate collagen regeneration.

Epidermal Growth Factor Applications

• Used in whitening essence to brighten skin tone
• Laboratory research

Reference:

1. Heck, Diane E.; Laskin, Debra L.; Gardner, Carol R.; Laskin, Jeffrey D. (1992) Epidermal growth factor suppresses nitric oxide and hydrogen peroxide production by keratinocytes. The potential role of nitric oxide in the regulation of wound healing. J Biol Chem 267:21277-80.
2. Grahn, Jennifer C.; Isseroff, R. Rivkah. (2004) Human melanocytes do not express EGF receptors. Journal of Investigative Dermatology, 123: 244-246.