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040-000-546 4-methyl-N3-[4-(3-pyridinyl)-2-pyrimidinyl]-1,3-Benzenediamine

4-methyl-N3-[4-(3-pyridinyl)-2-pyrimidinyl]-1,3-Benzenediamine
SKU: 040-000-546 Category:
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Type Active Pharmaceutical ingredient
Synonym 2-(5-Amino-2-methylanilino)-4-(3-pyridyl)pyrimidine;

N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine
CAS No. 152460-10-1
Chemical Formula C16H15N5
Packaging 1g, 5g, 10g, 25g, 100g, 500g, etc.
Form Yellow solid
Assay ≥98%
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4-[(4-Methyl-1-piperazinyl)methyl]benzoic Acid Dihydrochloride;

Dasatinib Monohydrate.
Description

Description

4-methyl-N3-[4-(3-pyridinyl)-2-pyrimidinyl]-1,3-Benzenediamine Introduction

4-methyl-N3-[4-(3-pyridinyl)-2-pyrimidinyl]-1,3-Benzenediamine is an intermediate of imatinib. Imatinib is a first-generation tyrosine kinase inhibitor, a drug for the treatment of chronic myeloid leukemia. It only kills BCR-ABL contained in myeloid cells, preventing cell proliferation and tumor formation, but has no effect on normal cells. It also inhibits PDGF-mediated tumors, including gliomas and prostate cancer.

4-methyl-N3-[4-(3-pyridinyl)-2-pyrimidinyl]-1,3-Benzenediamine Specification

Melting Point 133-135℃
Boiling Point 537.3±60.0℃
Form Yellow solid
Density 1.266±0.06 g/cm3
Packaging 1g, 5g, 10g, 25g, 100g, 500g, etc.

 

4-methyl-N3-[4-(3-pyridinyl)-2-pyrimidinyl]-1,3-Benzenediamine Applications

4-methyl-N3-[4-(3-pyridinyl)-2-pyrimidinyl]-1,3-Benzenediamine is an intermediate of imatinib.

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