Hyaluronic acid (HA) is widely distributed in the human body, including in the vitreous humor of the eyes, joints, umbilical cord, skin, and other areas. Its content in the body gradually decreases with age. Figure 1. Distribution of HA in the Human Body and Its Corresponding Concentrations The image above shows the distribution of hyaluronic … Continue reading
Over half of the hyaluronic acid (HA) in our bodies is found in skin, lungs, intestines, as well as in synovial fluid, umbilical cords, and blood. This material, which is closely tied to physiological activities in the human body, is highly biocompatible, naturally biodegradable, and water-absorbent. And it can also be easily modified. In recent … Continue reading
1. Low-Molecular-Weight and Oligomeric Hyaluronic Acid Hyaluronic acid is a natural linear polysaccharide occurring in the human body. Its molecular weight varies from several thousand to several million Daltons. High-molecular-weight hyaluronic acid (HMW-HA) has excellent moisture-retention and lubrication properties; thus, it can be widely used in cosmetics and medicine. However, recent research has revealed that … Continue reading
The rheological properties of hyaluronic acid refer to the scientific description of its flow and deformation behavior when subjected to forces, such as shear or stretching. 1. What is Rheology? Rheology is the science that studies the deformation and flow of matter. It bridges the gap between elasticity (like a spring, which can recover its … Continue reading
In June 2025, a controlled study presented at the International Hyaluronic Acid Conference 2025 in the United States showed that potassium hyaluronate (HA-K) performs better than sodium hyaluronate (HA-Na) in treating dry eye disease. By regulating the ionic balance of the tear film, HA-K can increase tear secretion by 22% and reduce corneal fluorescein staining … Continue reading
One of the most well-known functions of hyaluronic acid (HA) is moisturization. Additionally, HA can help reduce wrinkles and accelerate wound healing. However, some believe that while high molecular weight HA has anti-inflammatory effects, low molecular weight HA may trigger inflammatory reactions. But is this really true? Low Molecular Weight Hyaluronic Acid Penetrates Deep into … Continue reading
Hyaluronic acid gel is a multi-functional product. It moisturizes, repairs, and soothes the skin. 1. What is Hyaluronic Acid Gel? Hyaluronic acid gel is a gel-like product, like figure 1. Its key ingredient is hyaluronic acid (HA), which naturally found in our skin, joints, and eyes. HA can hold up to 1000 times its weight … Continue reading
When it comes to hyaluronic acid (HA), most people probably think of its use in skincare and joint treatments. SCC has also written many articles on these topics. But there’s more to it. Hyaluronic acid is now recognized as a key material in the development of new biomaterials in the biomedical field. Thanks to its … Continue reading
Hyaluronic acid (HA) is a naturally occurring glycosaminoglycan. It was first discovered as early as 1880, and it has been used for decades in orthopedics, ophthalmology, and dermatology. However, it is only in recent years that its unique value in periodontal tissue repair and regeneration has begun to be recognized. Molecular Properties of Hyaluronic Acid … Continue reading
Hyaluronic acid (HA) is a substance with applications ranging from skincare and beauty to medical and injection uses. Sodium hyaluronate is its sodium salt form, which is more stable and serves as the primary form in practical applications. HA exists in various forms, including powder, liquid, and gel. Among, powder being the most stable and … Continue reading
